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(3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine, also known as (3R,4S)-1-[benzyloxycarbonyl-4-(ethylamino)pyrrolidine], is a versatile organic compound that has found wide applications in the chemical industry.
This compound is a derivative of pyrrolidine, which is a four-membered heterocyclic ring containing a nitrogen atom.
Upstream Products
The upstream products of (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine are the raw materials required for its synthesis.
These raw materials are sourced from various chemical manufacturers and suppliers, and are subject to stringent quality control measures to ensure their purity and consistency.
One of the key raw materials required for the synthesis of (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine is benzyl bromide.
Benzyl bromide is a colorless liquid with a characteristic sweet odor, and is commonly used as a solvent and as a building block for the synthesis of various organic compounds.
Another raw material required for the synthesis of (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine is ethyl iodide, which is a yellow liquid with a characteristic ethyl odor.
Ethyl iodide is commonly used in organic synthesis as a reagent for the introduction of the iodine atom into a molecule.
Downstream Products
The downstream products of (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine are the various chemical products that can be derived from it.
One of the most common downstream products of (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine is the solvent (3R,4S)-1-((benzyloxy)carbonyl)-4-ethyl-N,N-dimethylamino)pyrrolidine, also known as N,N-dimethylformamide (DMF).
DMF is a colorless liquid with a characteristic odor, and is commonly used as a solvent and a catalyst in various chemical reactions.
Another downstream product of (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine is the pharmaceutical drug (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-2,5-dione, which is used for the treatment of certain types of cancer.
This compound is synthesized by the reduction of (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine using various chemical reagents and methods.
In addition to these specific downstream products, (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine can be also used as a building block for the synthesis of various other organic compounds, including polymers, dyes, and pigments.
Manufacturing Process
The manufacturing process of (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine involves several steps, including the synthesis of benzyl bromide, the reaction of ethyl iodide with benzyl bromide, and the reduction of the resulting compound to form (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine.
The synthesis of benzyl bromide involves the treatment of benzyl alcohol with hydrobromic acid, followed by the removal of water through distillation.
The reaction of ethyl iodide with benzyl bromide is carried out in the presence of a Lewis acid catalyst, such as aluminum chloride, to promote the reaction.
Finally, the reduction of the resulting compound is carried out using various reducing agents, such as lithium aluminum hydride or hydrogen in the presence of a