-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
The chemical industry plays a vital role in the global economy, providing the raw materials and intermediate chemicals needed to produce a wide range of products.
One important aspect of the chemical industry is the production of specialty chemicals, which are used in a variety of applications, from pharmaceuticals to agrochemicals to electronics.
One such specialty chemical is 3-chloro-6-pyrrolidin-1-yl-pyridazine, also known as N-chloro-4,6-dimethylpyridazine-2,3-diamine.
Upstream products
The production of 3-chloro-6-pyrrolidin-1-yl-pyridazine begins with the synthesis of its constituentbuilding blocks.
One of the key starting materials is 4,6-dimethylpyridazine-2,3-diamine, which is synthesized from dimethylformamide and piperazine.
The 4,6-dimethylpyridazine-2,3-diamine is then chlorinated using elemental chlorine or a chlorination reagent such as thionyl chloride to yield N-chloro-4,6-dimethylpyridazine-2,3-diamine.
Another important intermediate in the synthesis of 3-chloro-6-pyrrolidin-1-yl-pyridazine is 2-chloro-6-pyrrolidin-1-yl-pyridine.
This compound is synthesized by treating 2-aminopyridine with chloroform and hydrochloric acid to yield 2-chloro-6-pyrrolidin-1-yl-pyridine.
This intermediate can also be synthesized by treating pyridine with chloroform and hydrochloric acid.
Downstream products
Once the intermediate compounds have been synthesized, they are then converted into the final product, 3-chloro-6-pyrrolidin-1-yl-pyridazine, through a series of chemical reactions.
One common method for synthesizing 3-chloro-6-pyrrolidin-1-yl-pyridazine involves treating 2-chloro-6-pyrrolidin-1-yl-pyridine with anhydrous aluminum chloride under anhydrous conditions.
The resulting compound can then be further processed or used as is, depending on the intended application.
For example, 3-chloro-6-pyrrolidin-1-yl-pyridazine is sometimes used as a catalyst for the polymerization of polypropylene.
It is also used as an intermediate in the synthesis of other chemicals, such as agrochemicals or pharmaceuticals.
Regulatory considerations
As with all chemicals, the production and use of 3-chloro-6-pyrrolidin-1-yl-pyridazine are subject to a variety of regulations and standards.
The specific regulations that apply will depend on the intended use and the jurisdiction in which the chemical is being produced or used.
In the United States, for example, 3-chloro-6-pyrrolidin-1-yl-pyridazine is classified as a hazardous substance and is subject to the regulations of the Occupational Safety and Health Administration (OSHA) and the Environmental Protection Agency (EPA).
In addition to these regulatory requirements, there may also be specific guidelines or standards that apply to the production and use of 3-chloro-6-pyrrolidin-1-yl-pyridazine, depending on the intended use.
For example, the chemical may be subject to pharmacological or toxicological guidelines if it is being used in the development of a pharma