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3-Chloro-6-phenyl-pyridazin-4-ol, also known as CP 203, is an important intermediate chemical used in the production of various pharmaceuticals, agrochemicals, and other products in the chemical industry.
This compound can be synthesized through various methods, but one common route is through the oxidation of 3-chloro-6-phenyl-pyridazine using potassium permanganate.
One of the downstream products of CP 203 is the antibiotic fusidic acid, which is used to treat a variety of bacterial infections.
The synthesis of fusidic acid from CP 203 involves a series of chemical reactions, including an electrophilic substitution reaction, a reduction, and a dehydration.
The product is then purified through various methods, such as crystallization and chromatography, to obtain a pure sample of fusidic acid.
Another downstream product of CP 203 is the herbicide metribuzin, which is used to control weeds in crops such as soybeans, corn, and wheat.
The synthesis of metribuzin from CP 203 involves a series of chemical reactions, including a reduction, a halogenation, and a nitration.
The product is then purified through various methods, such as crystallization and chromatography, to obtain a pure sample of metribuzin.
In addition to these downstream products, CP 203 can also be used as an intermediate in the synthesis of other compounds.
For example, it can be converted into the antibiotic rifamycin SV through a series of chemical reactions, including a nitro group reduction and a series of electrophilic substitution reactions.
The production of CP 203 is an upstream process that involves several steps, including the synthesis of 3-chloro-6-phenyl-pyridazine, which is then oxidized using potassium permanganate to form CP 203.
The oxidation reaction is typically carried out in the presence of a solvent, such as acetonitrile or DMF, and a base, such as sodium hydroxide or potassium hydroxide, to facilitate the reaction.
The reaction is then quenched with a neutralizing agent, such as sodium bicarbonate or calcium carbonate, to stop the reaction.
The crude CP 203 product is then purified through various methods, such as crystallization and chromatography, to obtain a pure sample of the compound.
The purification process is important to remove any impurities that may have been introduced during the synthesis and oxidation steps.
The production of CP 203 is a complex process that requires careful control of the reaction conditions and purification steps to ensure the quality of the final product.
The purity of the CP 203 product is critical for the successful synthesis of downstream products such as fusidic acid and metribuzin.
In conclusion, CP 203 is an important intermediate chemical used in the production of various pharmaceuticals, agrochemicals, and other products in the chemical industry.
It can be synthesized through various methods, and its downstream products include the antibiotic fusidic acid and the herbicide metribuzin.
The production of CP 203 involves several steps, including the synthesis of 3-chloro-6-phenyl-pyridazine and its oxidation using potassium permanganate.
The crude CP 203 product is then purified through various methods to obtain a pure sample of the compound.
The purity of the CP 203 product is critical for the successful synthesis of downstream products.