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3-Bromo-6-methoxyquinoline is a chemical compound that is commonly used in the pharmaceutical and agrochemical industries.
It is a colorless to pale yellow solid that is soluble in water and organic solvents.
The compound is classified as a bromine intermediate and is used in the production of various active pharmaceutical ingredients (APIs) and agrochemicals.
In the chemical industry, upstream and downstream products refer to the various intermediates and end-products that are produced in a chemical manufacturing process.
For 3-bromo-6-methoxyquinoline, its upstream products include the raw materials required for its production, such as bromine and methoxyquinoline.
The downstream products, on the other hand, are the various APIs and agrochemicals that are produced using 3-bromo-6-methoxyquinoline as an intermediate.
One of the most important upstream products for 3-bromo-6-methoxyquinoline is bromine, which is used in the production of a wide range of chemicals, including flame retardants, water treatment chemicals, and photographic chemicals.
Methoxyquinoline, another upstream product, is used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
The production of 3-bromo-6-methoxyquinoline involves several steps, including bromination, methylation, and quinolination.
The bromination step involves the addition of bromine to a nitrogen-containing compound, such as phenol, to produce 2-bromo-6-methoxyquinoline.
This is followed by the methylation step, where methyl iodide is added to the product of the bromination step to produce 3-bromo-6-methoxyquinoline.
Finally, the quinolination step involves the addition of a quinoline molecule to the product of the methylation step to produce the final product, 3-bromo-6-methoxyquinoline.
The downstream products produced using 3-bromo-6-methoxyquinoline include a variety of APIs and agrochemicals.
One of the most important APIs is the anti-inflammatory drug celecoxib, which is used to treat pain, inflammation, and other symptoms associated with conditions such as rheumatoid arthritis, osteoarthritis, and acute pain.
Celecoxib is produced using 3-bromo-6-methoxyquinoline as an intermediate.
Another important downstream product is the herbicide glyphosate, which is widely used in agriculture to control weeds.
Glyphosate is produced using 3-bromo-6-methoxyquinoline as an intermediate in the production process.
Other downstream products produced using 3-bromo-6-methoxyquinoline include the fungicide imazalil, the insecticide chlorpyrifos, and the pharmaceutical ingredient acemetacin.
In conclusion, 3-bromo-6-methoxyquinoline is an important intermediate in the production of a variety of chemicals, including APIs and agrochemicals.
The compound is produced using a multi-step process that involves bromination, methylation, and quinolination.
The final product is used as an intermediate in the production of various downstream products, including celecoxib, glyphosate, imazalil, chlorpyrifos, and acemetacin.