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Introduction
In the chemical industry, the development of new compounds and molecules is a continuous process.
One such molecule that has garnered attention in recent years is 3-((3,5-Bis(trifluoromethyl)phenethoxy)(4-fluorophenyl)(morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one.
This molecule has unique properties that make it an attractive candidate for use in a variety of applications.
Upstream Products
The development of 3-((3,5-Bis(trifluoromethyl)phenethoxy)(4-fluorophenyl)(morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one involves a number of upstream products.
One of the key upstream products is 1,2,4-Triazole-5(4H)-one.
This compound is made by reacting ammonia with formaldehyde in the presence of a catalyst, such as iron powder.
The resulting compound is then treated with hydrazine to convert it into 1,2,4-triazole-5(4H)-one.
Another upstream product is 3,5-Bis(trifluoromethyl)phenethylamine.
This compound is made by reacting 3,5-Bis(trifluoromethyl)phenyl chloride with ammonia in the presence of a base, such as sodium hydroxide.
The resulting compound is then treated with trimethylsilyl azide to convert it into 3,5-Bis(trifluoromethyl)phenethylamine.
Downstream Products
The downstream products of 3-((3,5-Bis(trifluoromethyl)phenethoxy)(4-fluorophenyl)(morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one are numerous and diverse.
One of the key downstream products is 4-Fluoro-N-(3-((3,5-Bis(trifluoromethyl)phenethoxy)(morpholino)methyl)-1H-1,2,4-triazol-5-yl)phenyl)benzamide.
This compound is made by reacting 4-fluoro-N-(3-((3,5-Bis(trifluoromethyl)phenethoxy)(morpholino)methyl)-1H-1,2,4-triazol-5-yl)aniline with phenyl isocyanate.
Another downstream product is 3-((3,5-Bis(trifluoromethyl)phenethoxy)(4-fluorophenyl)(morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one itself.
This compound is made by reacting 3-((3,5-Bis(trifluoromethyl)phenethoxy)(4-fluorophenyl)(morpholino)methyl)amine with tributylphosphine diazomethane to form the triazole ring.
Applications of 3-((3,5-Bis(trifluoromethyl)phenethoxy)(4-fluorophenyl)(morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one
3-((3,5-Bis(trifluoromethyl)phenethoxy)(4-fluorophenyl)(morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one has a number of attractive properties that make it suitable for use in a variety of applications.
For example, it has been shown to have potent antibacterial activity against a number of Gram-positive and Gram-negative bacterial strains, including Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa.
In addition to its antibacterial activity, 3-((3,5-Bis(trifluoromethyl)phenethoxy)(4-fluorophen
