The Upstream and Downstream products of 2H-Pyrrolo[3,2-c]pyridin-2-one,1,3-dihydro-(9CI)

2H-Pyrrolo[3,2-c]pyridin-2-one, also known as 9CI, is a key intermediate in the production of various chemical products in the pharmaceutical and agrochemical industries.
The upstream products of 9CI are the raw materials required for its production, while the downstream products are the final products that are derived from 9CI.

The upstream products for the production of 9CI include precursors such as pyridine-2,5-dione and 2H-pyrrolo[3,2-c]pyridine-2,5-dione.
These precursors are derived from chemical reactions involving phenyl acetate, malonic acid, and other starting materials.
The production of 9CI involves several steps, including a Mannich reaction, a hydroboration-oxidation reaction, and a hydrolysis reaction.
The raw materials required for these reactions include borane, hydrogen peroxide, sodium hydroxide, and other reagents.

Once the upstream products have been obtained, the next step is to produce 9CI through a series of chemical reactions.
The production process involves several steps, including a Mannich reaction, a hydroboration-oxidation reaction, and a hydrolysis reaction.
The Mannich reaction involves the condensation of pyridine-2,5-dione and formaldehyde in the presence of an acid catalyst such as sulfuric acid.
The product of this reaction is then subjected to a hydroboration-oxidation reaction, where borane and hydrogen peroxide are added to the reaction mixture.
Finally, the product is hydrolyzed using sodium hydroxide to produce 9CI.

The downstream products of 9CI include a range of pharmaceutical and agrochemical products.
One of the most common downstream products is 2-(2-hydroxyethylamino)-5-(2-methoxyethylamino)-1H-pyrrole-3-carboxamide, which is used as an intermediate in the production of certain types of antidepressants.
Another downstream product is 2-[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1]benzoxazepin-9-yl]amino]propanamide, which is used in the production of certain types of pesticides.

In conclusion, 9CI is an important intermediate in the production of various pharmaceutical and agrochemical products.
The upstream products for its production include pyridine-2,5-dione and 2H-pyrrolo[3,2-c]pyridine-2,5-dione, while the downstream products include a range of pharmaceutical and agrochemical products.
The production of 9CI involves several steps, including a Mannich reaction, a hydroboration-oxidation reaction, and a hydrolysis reaction.
The chemical industry heavily relies on the production of intermediates such as 9CI to supply the demand for various chemical products, including pharmaceuticals and pesticides.