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Introduction
In the chemical industry, the production of a single chemical compound often involves a series of chemical reactions, each step of which produces a specific product, known as an intermediate.
These intermediates can then be further processed to produce the final product, which is known as the downstream product.
Alternatively, the intermediates can be used as starting materials for the production of other chemicals, known as upstream products.
In this article, we will focus on the upstream and downstream products of 2-(methylthio)-5-(tributylstannyl)pyrimidine, a synthetic chemical compound used in various applications.
Upstream Products
The production of 2-(methylthio)-5-(tributylstannyl)pyrimidine typically involves several upstream chemical reactions, each of which produces a specific intermediate product.
The starting material for the production of this compound is usually a precursor molecule, such as 2-chloromethyl-5-(tributylstannyl)pyrimidine.
This molecule can be synthesized through a series of chemical reactions involving halogenation, nitration, and sulfuration.
One upstream product of the production of 2-(methylthio)-5-(tributylstannyl)pyrimidine is 2-chloromethyl-5-(di-t-butylstanny)pyrimidine, which is obtained by treating 2-chloromethyl-5-(tributylstanny)pyrimidine with a reducing agent, such as hydrogen in the presence of a metal catalyst.
This reaction converts the chlorine atom in the precursor molecule to a hydrogen atom, and results in the formation of a new C-H bond.
Another upstream product of the production of 2-(methylthio)-5-(tributylstannyl)pyrimidine is 2-(methylthio)-5-(tributylstanny)pyrimidine itself, which can be produced through a series of chemical reactions involving sulfurization, nitration, and halogenation of the precursor molecule.
This compound is an intermediate product that can be used in the production of other chemicals, or it can be further processed to produce the final product.
Downstream Products
The production of 2-(methylthio)-5-(tributylstannyl)pyrimidine typically involves several downstream chemical reactions, each of which produces a specific downstream product.
The first step in the downstream processing of this compound is usually its purification, which is typically done by chromatography or crystallization.
The purified compound is then used as a starting material for the production of the final product.
One downstream product of the production of 2-(methylthio)-5-(tributylstannyl)pyrimidine is 2-(methylthio)imidazo[1,2-d]pyrimidine, which is obtained by treating 2-(methylthio)-5-(tributylstannyl)pyrimidine with a reducing agent, such as lithium aluminum hydride.
This reaction converts the nitro group in the compound to an amino group, resulting in the formation of a new C-N bond.
Another downstream product of the production of 2-(methylthio)-5-(tributylstannyl)pyrimidine is 2-(methylthio)pyrimidine-5-carboxylic acid, which is obtained by treating 2-(methylthio)-5-(tributylstannyl)pyrimidine with a strong acid, such as sulfuric acid.
This reaction converts the nitro group in the compound to a carboxylic acid group, resulting in the formation of a new C-O bond.