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2-Bromo-N-(fur-2-ylmethyl)benzenesulphonamide, commonly referred to as BFBS, is a chemical compound that is widely used in the pharmaceutical and agrochemical industries.
It is an important intermediate in the production of various drugs and pesticides, and its demand is expected to grow in the coming years.
In this article, we will discuss the upstream and downstream products of BFBS, and how the chemical industry utilizes this compound.
Upstream Products
The upstream products of BFBS are the raw materials and intermediates used in its production.
The primary raw material for the production of BFBS is 2-bromobenzenesulfonic acid, which is commonly sourced from China, India, and other countries with a strong chemical industry.
This acid is reacted with furan-2-ylmethanamine, which is derived from the reaction of dimethylformamide and ammonia, to produce BFBS.
Other raw materials used in the production of BFBS include sodium hydroxide, water, and solvents such as dichloromethane and ethyl acetate.
Downstream Products
The downstream products of BFBS are the final products that are produced using this compound as an intermediate.
BFBS is a versatile intermediate and can be used to produce a wide range of drugs and pesticides.
Some of the most important downstream products of BFBS include:
- Anti-malarial drugs: BFBS is used in the production of several important anti-malarial drugs, including mefloquine, lumefantrine, and halofantrine.
These drugs are used to treat malaria, a disease that affects millions of people worldwide each year. - Anti-TB drugs: BFBS is also used in the production of anti-TB drugs, including first-line TB drugs such as isoniazid and rifampicin.
These drugs are important in the treatment of tuberculosis, a disease that remains a major global health problem. - Herbicides: BFBS is used in the production of several herbicides, including tribenuron-methyl and bentazon.
These herbicides are used to control weeds in agricultural fields and other areas. - Insecticides: BFBS is also used in the production of insecticides, including pyrethroids and carbamates.
These insecticides are used to control pests in agricultural fields and other areas.
Chemical Industry Utilization
The chemical industry utilizes BFBS in a variety of ways, including the production of pharmaceuticals and agrochemicals.
The demand for BFBS is expected to grow in the coming years, driven by the increasing demand for these products.
The production of BFBS is a complex process that involves several steps, including the synthesis of 2-bromobenzenesulfonic acid, the reaction of furan-2-ylmethanamine with this acid, and the purification and isolation of the resulting product.
The production of BFBS is a highly technical and specialized process that requires expert knowledge and state-of-the-art equipment.
The production of BFBS is regulated by various government agencies, including the U.
S.
Food and Drug Administration (FDA) and the European Medicines Agency (EMA), to ensure that it is produced in a safe and effective manner.
In conclusion, 2-bromo-N-(fur-2-ylmethyl)benzenesulphonamide, commonly known as BFBS, is an important intermediate in the production of various drugs and pesticides.
Its use in these products has a significant impact on the pharmaceutical and agrochemical industries, and its demand is expected to grow in the coming years.
The production of BFBS is a