The Upstream and Downstream products of 2-AMINO-ISONICOTINIC ACID ETHYL ESTER

2-Amino-Isonicotinic Acid Ethyl Ester: An Overview of its Upstream and Downstream Products in the Chemical Industry

2-Amino-isonicotinic acid ethyl ester (AIEE) is an important intermediate chemical that is widely used in the production of various end products in the chemical industry.
AIEE is synthesized through a complex manufacturing process that involves several steps and requires the use of several different chemicals and reagents.
In this article, we will discuss the upstream and downstream products of AIEE in the chemical industry.

Upstream Products of 2-Amino-Isonicotinic Acid Ethyl Ester

The upstream products of AIEE are the raw materials and intermediates that are required for its synthesis.
The primary upstream products of AIEE include alpha-amino acids, such as L-lysine and L-phenylalanine, and isonicotinic acid.

Alpha-amino acids are essential building blocks in the synthesis of proteins and are widely used in the food and beverage industry, animal feed industry, and pharmaceutical industry.
Isonicotinic acid, on the other hand, is used as a precursor in the synthesis of AIEE and is also used as an intermediate in the production of other chemicals, such as agricultural chemicals and dyes.

Downstream Products of 2-Amino-Isonicotinic Acid Ethyl Ester

The downstream products of AIEE are the end products that are produced using AIEE as an intermediate or a final product.
The primary downstream products of AIEE include agricultural chemicals, pharmaceuticals, and personal care products.

AIEE is used as an intermediate in the production of agricultural chemicals, such as herbicides and insecticides.
It is also used in the production of pharmaceuticals, such as anti-inflammatory drugs and analgesics.
Additionally, AIEE is used in the production of personal care products, such as shampoos, soaps, and lotions.

Chemical Synthesis of 2-Amino-Isonicotinic Acid Ethyl Ester

The chemical synthesis of AIEE involves several steps, including the synthesis of alpha-amino acids, the hydrolysis of isonicotinic acid, and the esterification of alpha-amino acids with isonicotinic acid.
The steps involved in the synthesis of AIEE are as follows:

Step 1: Synthesis of alpha-amino acids

Alpha-amino acids are synthesized through a variety of methods, including chemical synthesis and biological synthesis.
Chemical synthesis involves the reaction of ammonia with a variety of organic acids, such as malonic acid, to form alpha-amino acids.

Step 2: Hydrolysis of isonicotinic acid

Isonicotinic acid is hydrolyzed to form nicotinic acid and isonipecotic acid.
This step is carried out using hydrolytic agents, such as alkali, to break down the ester bond between the carboxylic acid group and the alcohol group.

Step 3: Esterification of alpha-amino acids with isonicotinic acid

The esterification of alpha-amino acids with isonicotinic acid is carried out by reacting the amino acid with isonicotinic acid in the presence of a condensing agent, such as a carboxylic acid or a sulfuric acid catalyst.

Step 4: Dehydration of the resulting intermediate

The intermediate produced in step 3 is further dehydrated using dehydrating agents, such as sodium sulfate or calcium chloride, to