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    Home > Medical News > Medical World News > The Upstream and Downstream products of 2-Amino-5-methyl-4,6(1H,5H)-pyrimidinedione

    The Upstream and Downstream products of 2-Amino-5-methyl-4,6(1H,5H)-pyrimidinedione

    • Last Update: 2023-05-10
    • Source: Internet
    • Author: User
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    2-Amino-5-methyl-4,6(1H,5H)-pyrimidinedione is a white or practically white, crystalline powder with a melting point of 268-270°C.
    It is soluble in water and methanol, but insoluble in ethanol and ether.
    This compound is commonly used as an intermediate in the synthesis of various pharmaceuticals, dyes, and optical brighteners.


    One of the most common uses of 2-amino-5-methyl-4,6(1H,5H)-pyrimidinedione is in the synthesis of the anti-hypertensive drug, Captopril.
    Captopril is a peptide derivative that is used to treat hypertension and congestive heart failure.
    It is also used in the synthesis of other pharmaceuticals such as ice-minus, a vasodilator used to treat angina pectoris.


    2-amino-5-methyl-4,6(1H,5H)-pyrimidinedione is also used as an intermediate in the synthesis of certain dyes.
    For example, it is used in the synthesis of Basic Red 76, a red dye used in printing ink, textiles, and paper production.
    It is also used in the synthesis of Rongalite, a red dye used in the production of plastics and fibers.


    Another application of 2-amino-5-methyl-4,6(1H,5H)-pyrimidinedione is in the synthesis of optical brighteners.
    Optical brighteners are compounds that absorb ultraviolet light and re-emit it as blue light.
    This property makes them useful as brightening agents in textiles, paper, and other products.


    The upstream products of 2-amino-5-methyl-4,6(1H,5H)-pyrimidinedione are the raw materials used in its synthesis.
    The most common upstream products include 2-chloro-5-methyl-4,6-benzenedione and 5-methyl-2-(4-nitrophenyl)-4,6-(1H,5H)-pyrimidinedione.
    These compounds are used as intermediates in the synthesis of 2-amino-5-methyl-4,6(1H,5H)-pyrimidinedione.


    The downstream products of 2-amino-5-methyl-4,6(1H,5H)-pyrimidinedione include Captopril, ice-minus, Basic Red 76, Rongalite, and optical brighteners.
    These compounds are used in various industries such as pharmaceuticals, textiles, paper production, and plastics.


    In conclusion, 2-amino-5-methyl-4,6(1H,5H)-pyrimidinedione is an important intermediate in the synthesis of various pharmaceuticals, dyes, and optical brighteners.
    It is synthesized from upstream products such as 2-chloro-5-methyl-4,6-benzenedione and 5-methyl-2-(4-nitrophenyl)-4,6-(1H,5H)-pyrimidinedione.
    The downstream products of 2-amino-5-methyl-4,6(1H,5H)-pyrimidinedione include Captopril, ice-minus, Basic Red 76, Rongalite, and optical brighteners, which are used in various industries such as pharmaceuticals, textiles, paper production, and plastics.



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