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2-Amino-5-bromopyrimidin-4-ol hydrobromide, also known as APBOH or 2-ABP, is an organic compound commonly used in the chemical industry.
It is an intermediate product that is widely used in the production of various pharmaceuticals, agrochemicals, and other chemical products.
Upstream Products
The production of 2-amino-5-bromopyrimidin-4-ol hydrobromide involves several upstream processes, including the synthesis of the intermediate compound 2-amino-5-bromopyrimidine and its subsequent hydrobromination.
2-Amino-5-bromopyrimidine is synthesized by treating 2-aminopyrimidine with bromine gas under appropriate conditions.
This reaction results in the formation of the intermediate compound 2-bromo-5-aminopyrimidine.
The next step involves the hydrolysis of the bromine to yield 2-amino-5-bromopyrimidine.
This compound is then subjected to hydrobromination, where it is treated with hydrogen bromide gas, resulting in the formation of 2-amino-5-bromopyrimidin-4-ol hydrobromide.
Downstream Products
2-Amino-5-bromopyrimidin-4-ol hydrobromide is a versatile intermediate compound that can be transformed into a variety of downstream products through a series of chemical reactions.
One common use of this compound is in the production of pharmaceuticals, where it is used as a precursor to a variety of drugs, including anti-tuberculosis agents, anti-malarials, and anti-cancer drugs.
Another application of 2-amino-5-bromopyrimidin-4-ol hydrobromide is in the production of agrochemicals, including herbicides and pesticides.
In these applications, the compound is used as a starting material for the synthesis of active ingredients that are effective in controlling weeds and pests in crops.
2-Amino-5-bromopyrimidin-4-ol hydrobromide is also used in the production of other chemical products, such as dyes, fragrances, and cosmetics.
In these applications, the compound serves as a building block for the synthesis of various chemicals that are used in these industries.
Chemical Properties
2-Amino-5-bromopyrimidin-4-ol hydrobromide is a water-soluble, white to off-white, crystalline solid.
It has a strong, unpleasant odor and is highly soluble in water and most organic solvents.
The compound is hygroscopic and should be stored in a cool, dry place to prevent moisture contamination.
2-Amino-5-bromopyrimidin-4-ol hydrobromide is a sensitive compound that can undergo hydrolysis in the presence of moisture or acidic conditions.
It is also sensitive to oxidizing agents and should be stored away from reducing agents.
The compound is also subject to thermal degradation and should be stored away from heat and direct sunlight.
Purification and Isolation
2-Amino-5-bromopyrimidin-4-ol hydrobromide can be purified and isolated using various techniques, depending on its intended use.
In the production of pharmaceuticals, for example, the compound may need to be purified to a high degree to ensure its purity and stability.
This can be achieved using techniques such as crystallization, chromatography, and recrystallization.
In the production of agrochemicals and other chemical products, the purity of 2
