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    Home > Active Ingredient News > Drugs Articles > The Upstream and Downstream products of 2,5-Diaminobenzonitrile

    The Upstream and Downstream products of 2,5-Diaminobenzonitrile

    • Last Update: 2023-04-26
    • Source: Internet
    • Author: User
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    2,5-Diaminobenzonitrile (2,5-DABN) is an important chemical intermediate that is widely used in the production of various chemicals, drugs, and materials.
    The upstream and downstream products of 2,5-DABN can vary depending on the specific applications and end-use products.


    Upstream Products


    The upstream products of 2,5-DABN are primarily the raw materials required for its production.
    These raw materials include nitrobenzene, aniline, and ammonia.
    Nitrobenzene is the primary precursor for the synthesis of 2,5-DABN and is obtained by nitrating benzene in the presence of a strong acid catalyst.
    Aniline is another important precursor that is converted into nitrobenzene through a series of chemical reactions.
    Ammonia is used as a reagent in the final step of the synthesis of 2,5-DABN.


    Downstream Products


    The downstream products of 2,5-DABN are the chemicals, drugs, and materials that are produced using 2,5-DABN as an intermediate.
    The most common downstream products of 2,5-DABN include:


    1. Polyfunctional amides: 2,5-DABN is used as a precursor for the production of polyfunctional amides, which are important building blocks for the production of various polymers and materials.
    2. Heterocyclic compounds: 2,5-DABN is converted into a range of heterocyclic compounds, including pyridines, pyrimidines, and indoles, that are used in the production of drugs, agrochemicals, and other chemicals.
    3. Pharmaceuticals: 2,5-DABN is used in the production of various pharmaceuticals, including anti-asthmatic agents, antibiotics, and anti-cancer drugs.
    4. Polyurethanes: 2,5-DABN is used as a building block for the production of polyurethanes, which are important materials used in a wide range of applications, including adhesives, coatings, and foams.
    5. Dyes and pigments: 2,5-DABN is used as an intermediate in the production of various dyes and pigments, including azo dyes and anthraquinones.

    Manufacturing Process


    The production of 2,5-DABN involves several steps, including nitration, oxidation, and reduction.
    The manufacturing process can be summarized as follows:


    1. Nitration: Nitrobenzene is prepared by nitrating benzene in the presence of a strong acid catalyst, such as sulfuric acid or nitric acid.
      The reaction is carried out at a temperature of around 80-100°C and requires a careful control of the reaction conditions to ensure optimal yield and purity.
    2. Oxidation: The nitrobenzene obtained from the nitration step is then oxidized using oxygen or hydrogen peroxide to produce aniline.
      The oxidation reaction is typically carried out in the presence of a solvent, such as water or acetone, and requires careful control of the reaction conditions to avoid unwanted side reactions.
    3. Reduction: The aniline obtained from the oxidation step is then reduced using a reducing agent, such as hydrogen gas or lithium aluminum hydride (LAH), to produce 2,5-DABN.
      The reduction reaction is typically carried out in the presence of a solvent, such as ethanol or methanol, and requires careful control of the reaction conditions to ensure optimal yield and purity.

    Industrial Production


    2,5-DABN is produced on a large scale in the chemical industry using various manufacturing processes, including batch, continuous, and flow processes.
    The choice of the manufacturing process depends on several factors, including the scale of production, the purity of the product, and the cost of production.
    Batch processes are typically used for small-scale production, while continuous and flow processes are used for large-scale production.


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