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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, commonly known as pyrazole, is an important organic compound used in various applications in the chemical industry.
Pyrazole can be synthesized through several methods, and one of the most common methods involves the diazotization of 2-methyl-1,3-benzoxazepine.
One of the primary applications of pyrazole is as a building block for the synthesis of various chemical products.
Pyrazole can be converted into a variety of derivatives, such as 1,2-bis(2,5-dimethyl-3-methoxyphenyl)ethane, 2-methyl-1-[4-(2-methyl-3-pyrazol-5-ylphenyl)butoxy]-3-(2,5-dimethyl-3-methoxyphenyl)propan-2-ol, and 2-(3,4-dimethylphenyl)-1H-pyrazol-3-amine.
These derivatives can be used as intermediates for the production of a range of chemical products, including dyes, pharmaceuticals, and agrochemicals.
Pyrazole is also used as a corrosion inhibitor in industrial applications.
It can be added to cooling water systems to prevent the corrosion of metal components.
Pyrazole has shown excellent compatibility with several types of metal, including carbon steel, stainless steel, and copper, and can be used to protect these metals from corrosion in various environments.
Another application of pyrazole is in the production of antioxidants.
Pyrazole derivatives can act as antioxidants, which can protect against the degradation of plastics and other materials due to oxidative stress.
Pyrazole antioxidants are commonly used in the production of polymers, including polyolefins, polyvinyl chloride, and polyester.
Pyrazole is also used in the production of pharmaceuticals.
It can be used as an intermediate in the synthesis of various drugs, including antibiotics, anti-inflammatory drugs, and anti-cancer drugs.
For example, pyrazole can be converted into 1-(2,5-dimethyl-3-pyrazol-4-yl)-4-(2-methyl-1,3-oxazolidin-3-yl)benzene, which is used as an intermediate in the synthesis of the anticancer drug irinotecan.
Pyrazole is also used in the production of agrochemicals.
It can be used as a precursor for the synthesis of herbicides, insecticides, and fungicides.
For example, pyrazole can be converted into 3,6-dichloro-2-pyrazoline, which is used as an intermediate in the production of the herbicide imazamox.
In addition to its various applications, pyrazole is also known for its unique physical and chemical properties.
Pyrazole is a white or off-white solid that has a high melting point and a boiling point of approximately 276°C.
It is also soluble in various solvents, including water, ethanol, and benzene.
Pyrazole has a pungent, unpleasant odor and is classified as a Category 3 carcinogen by the International Agency for Research on Cancer.
Overall, pyrazole is an important compound in the chemical industry with a wide range of applications.
Its versatility as a building block for the synthesis of various chemical products, its use as a corrosion inhibitor, and its application in the production of antioxidants, pharmaceuticals, and agrochemicals make it a valuable tool in the chemical industry