The Upstream and Downstream products of 2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide

2-(1H-indazol-6-ylthio)-N-Methyl-Benzamide is a synthetic chemical compound that is commonly used as an intermediate in the production of various chemicals and pharmaceuticals.
The compound is synthesized by combining N-methylbenzamide with 1H-indazole-6-thiol in the presence of a suitable catalyst.

The upstream products required for the synthesis of 2-(1H-indazol-6-ylthio)-N-Methyl-Benzamide include N-methylbenzamide, 1H-indazole-6-thiol, and the catalyst used for the reaction.
These products are typically sourced from chemical suppliers or synthesized in-house using widely available starting materials.

The downstream products of 2-(1H-indazol-6-ylthio)-N-Methyl-Benzamide include a range of chemicals and pharmaceuticals that are used in various applications.
One of the most common downstream products is the anti-inflammatory drug celecoxib, which is used to treat pain, inflammation, and other symptoms associated with conditions such as arthritis and gout.
Other downstream products include anti-cancer drugs, antibiotics, and anti-viral agents.

The production of 2-(1H-indazol-6-ylthio)-N-Methyl-Benzamide typically involves a multi-step process that involves several intermediate steps.
The process typically involves the following steps:

1. Synthesis of N-methylbenzamide: This compound is synthesized by reacting benzaldehyde with methyl amine in the presence of a strong acid catalyst, such as hydrochloric acid.
   
2. Synthesis of 1H-indazole-6-thiol: This compound is synthesized by reacting indazole with a thiolating reagent, such as hydrogen sulfide or a mercaptan, in the presence of a catalyst, such as copper sulfate.
   
3. Synthesis of 2-(1H-indazol-6-ylthio)-N-Methyl-Benzamide: This compound is synthesized by combining N-methylbenzamide with 1H-indazole-6-thiol in the presence of a catalyst, such as palladium on coal.
   

The synthesis of 2-(1H-indazol-6-ylthio)-N-Methyl-Benzamide typically involves a multistep process, with each step requiring careful control of reaction conditions, such as temperature, pressure, and the use of appropriate solvents and catalysts.
The purity of the final product is typically monitored using a range of analytical techniques, such as high-performance liquid chromatography (HPLC) or gas chromatography (GC).

The production of 2-(1H-indazol-6-ylthio)-N-Methyl-Benzamide is a complex and multistep process that involves several intermediate steps.
The process requires careful control of reaction conditions and the use of appropriate equipment and reagents.
The downstream products of 2-(1H-indazol-6-ylthio)-N-Methyl-Benzamide include a range of chemicals and pharmaceuticals that are used in various applications.
The production of these downstream products requires careful control of the synthesis and purification processes to ensure the quality and efficacy of the final product.