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1-(3-Amino-pyridin-4-yl)-ethanone, also known as APET, is an important intermediate chemical used in the production of various pharmaceuticals, agrochemicals, and other chemical products.
The chemical industry is a vast and complex system that involves the conversion of raw materials into a variety of products, and APET is an essential component of this process.
In this article, we will explore the upstream and downstream products of 1-(3-amino-pyridin-4-yl)-ethanone, highlighting the key players and processes involved in the production and use of this important chemical intermediate.
Upstream Products
The upstream products of 1-(3-amino-pyridin-4-yl)-ethanone are the raw materials required for its production.
These raw materials include various chemicals, such as acetonitrile, hydroxyquinoline, and 4-chloro-1-phenyl-1,2-diamine.
The production of these raw materials involves various chemical reactions, such as condensation, substitution, and reduction reactions.
The production of 4-chloro-1-phenyl-1,2-diamine, a key upstream product for the production of APET, involves the reaction of chlorobenzene with para-aminophenol in the presence of a solvent, such as toluene or xylene.
This reaction generates 4-chloro-1-phenyl-1,2-diamine, which is further transformed into APET through a series of chemical reactions.
Downstream Products
The downstream products of 1-(3-amino-pyridin-4-yl)-ethanone are the chemical products generated from its production.
APET is used as an intermediate in the production of various pharmaceuticals, such as antihistamines and anti-depressants, as well as in the production of agrochemicals and other chemical products.
One of the key downstream products of APET is the antihistamine drug, Cetirizine.
Cetirizine is used to treat allergy symptoms, such as runny nose, sneezing, and itching.
The production of Cetirizine involves the reaction of APET with other chemicals, such as hydroxypropyl cellulose and xylitol, in the presence of solvents, such as acetonitrile and water.
This reaction generates Cetirizine, which is then purified and packaged for commercial use.
Another important downstream product of APET is the anti-depressant drug, Amitriptyline.
Amitriptyline is used to treat depression and anxiety disorders, and its production involves the reaction of APET with other chemicals, such as chloroform and sodium hydroxide, in the presence of solvents, such as ether and benzene.
This reaction generates Amitriptyline, which is then purified and packaged for commercial use.
In addition to its use in the production of pharmaceuticals, APET is also used in the production of agrochemicals, such as herbicides and insecticides.
These chemicals are used to control weeds and pests in agricultural settings, and their production involves the use of various chemical reactions and processes.
The Value Chain
The value chain of the chemical industry involves the conversion of raw materials into finished products, with APET as an important intermediate chemical.
The value chain involves various players, such as raw material suppliers, chemical manufacturers, distributors, and end-users.
Raw material suppliers are responsible for the production and supply of the various chemicals used in the production of APET.
These suppliers may be large chemical companies or small independent producers, and they play a critical role in ensuring a stable supply of raw materials for the chemical industry.
Chemical manufacturers are responsible for the production of APET and other chemical