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1-(2-Fluoro-phenyl)-3-methyl-butan-1-one, commonly known as 2-fluoro-methyl-butan-1-one, is a type of organic compound that is commonly used as a solvent, reactive intermediate, and building block in the chemical industry.
It is an important raw material in the production of various chemical products, including pharmaceuticals, agrochemicals, cosmetics, and other specialty chemicals.
Upstream Products
The upstream products of 2-fluoro-methyl-butan-1-one are mainly raw materials used in the production of the compound.
These raw materials include 2-fluoro-phenyl-propan-1-one, 3-methyl-butan-1-one, and other reactive intermediates.
2-Fluoro-phenyl-propan-1-one is a common precursor used in the production of 2-fluoro-methyl-butan-1-one.
The compound is synthesized from 2-fluoro-anisole, which is reacted with propylene in the presence of a catalyst such as aluminum chloride.
The reaction produces 2-fluoro-phenyl-propan-1-one, which can then be further transformed into 2-fluoro-methyl-butan-1-one through a series of chemical reactions.
3-Methyl-butan-1-one is another raw material used in the production of 2-fluoro-methyl-butan-1-one.
The compound is synthesized from 3-methyl-butyl-chloride, which is reacted with sodium hydride in the presence of a solvent such as THF.
The reaction produces 3-methyl-butan-1-one, which can then be transformed into 2-fluoro-methyl-butan-1-one through a series of chemical reactions.
Downstream Products
The downstream products of 2-fluoro-methyl-butan-1-one are mainly chemical products that are derived from the compound.
These products include intermediates, reagents, and final products used in a variety of applications.
One of the most common downstream products of 2-fluoro-methyl-butan-1-one is N-[(1R)-1-[(2S)-2-fluoro-1-(2-methoxy-2H-chromen-3-yl)-3-oxo-propanamido]-1,2,3,4-tetrahydro-quinolin-6-yl]-acetamide, which is used in the production of antibiotics.
The compound is synthesized from 2-fluoro-methyl-butan-1-one and several other reagents, and it is used as a key intermediate in the production of antibiotics such as eravacycline.
Another important downstream product of 2-fluoro-methyl-butan-1-one is 2-fluoro-methyl-butan-1-one itself, which is used as a solvent and reactive intermediate in a variety of applications.
The compound is commonly used in the production of chemicals such as agrochemicals, pharmaceuticals, and other specialty chemicals.
Chemical Synthesis of 2-Fluoro-methyl-butan-1-one
The chemical synthesis of 2-fluoro-methyl-butan-1-one typically involves several steps, including the synthesis of 2-fluoro-phenyl-propan-1-one, the synthesis of 3-methyl-butan-1-one, and the transformation of these intermediates into 2-fluoro-methyl-butan-1-one.
The synthesis of 2-fluoro-phenyl-propan-1-one typically involves the reaction of 2-fluoro-anisole with propylene in the presence of a catalyst such as aluminum chloride.
The reaction produces 2-fluoro-phenyl-propan-1-one, which
