The team of Professor Ge Wupeng from the College of Food Science, Northwest A & F University has made new progress in analyzing the lipidomic characteristics of breast milk and small varieties of characteristic milk

Recently, the team of Professor Ge Wupeng of Northwest A & F University published an online publication entitled "Characterization and comparison of lipids from human and ewe colostrum ba" in the international food field TOP journal "Food Chemistry" sed on lipidomics analysis", the first author of the paper is Wang Shuangshuang, a 2020 doctoral student, and the corresponding authors are Professor Ge Wupeng and Associate Professor
Zhang Jiaying.

 

Colostrum is essential for the development of the immune system of infants and young children, protecting them from allergies and chronic diseases, and has a protective effect
on infants and young children early in life.
However, problems such as low colostrum production or allergy to breast milk itself in infants and young children are encountered in human colostrum feeding, making it difficult to achieve sustainable and safe colostrum feeding
.
Therefore, functional dairy products containing different mammalian colostrums are suitable alternatives
for infants who cannot breastfeed human colostrum.
Sheep milk is a high-quality small variety of characteristic milk source that has gradually attracted attention, because of its rich nutrition and distinctive characteristics, it has gradually attracted the attention of researchers at home and abroad, and its colostrum is rich in immunoglobulins and peptide components, which has great potential
in the development of functional dairy products and infant formula.
Therefore, for the development of functional dairy products and infant formula, a deeper understanding of the difference between human and ewe colostrum is essential
.
This study aims to comprehensively identify and quantify lipids in human and ewe colostrum by utilizing quantitative lipidomics and screening and validating significantly different lipids and potential lipid biomarkers to distinguish between two types of colostrum
.
In this study, the lipid composition of human milk colostrum and sheep colostrum was analyzed based on quantitative lipidomics technology of ultra-performance liquid chromatography-triple quadrupole mass spectrometry, and a total of 1004 lipid molecules
of 26 subclasses were identified.
A total of 173 significantly different lipids
were screened for P < 0.
0001, VIP> 1.
1, FC≥2, or ≤0.
5.
In this study, a total of 10 major lipid metabolism pathways including sphingolipid metabolism and glycerophospholipid metabolism were detected, which has important guiding significance
for better understanding the lipid composition of human milk and sheep milk and the development of related functional dairy products in the colostrum stage.
This result is expected to provide important information
for assessing the nutritional value of human and ewe colostrum.
In addition, this research is expected to provide insight
into the potential direction of introducing ewe colostrum into the early life stages of commercial infant formula.

 

The research was supported
by the Key R&D Program of Shaanxi Province (2021ZDLNY02-09) and the cooperation of Northwest A & F University to build Jinchang Meat and Sheep Experimental Demonstration Base (Z222021501, K4030220448, K4030220449).

 

Original link: https://doi.
org/10.
1016/j.
foodchem.
2022.
133998