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N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide methanesulfonate is an organic compound that is commonly used in the chemical industry.
This compound is a synthetic intermediate that is used in the production of a variety of chemicals and pharmaceuticals.
The synthetic routes of N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide methanesulfonate can be classified into three main categories: synthesis via conventional methods, synthesis via green chemistry methods, and synthesis via biotechnology methods.
In this article, we will discuss each of these synthetic routes in more detail.
Conventional Synthetic Routes
The conventional synthetic routes of N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide methanesulfonate involve the use of traditional chemical synthesis methods.
These methods typically involve the use of hazardous reagents and conditions, and can be environmentally unfriendly.
One of the most common conventional synthetic routes of N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide methanesulfonate involves the use of a process called "Schiff's base condensation.
" This process involves the reaction of a primary amine, such as 4-pyridinylmethylamine, with a carbonyl compound, such as cyanocyclopentanone.
The resulting Schiff's base is then condensed with another equivalent of the carbonyl compound to form the desired product.
Another conventional synthetic route involves the use of a process called "Hydrolysis of N-Bromosuccinimide Ester.
" This process involves the reaction of N-bromosuccinimide with an amine, such as 4-pyridinylmethylamine, to form an N-bromosuccinimide ester.
The ester is then hydrolyzed to form the desired product.
Green Chemistry Synthetic Routes
Green chemistry is a discipline that seeks to improve the environmental and health performance of chemical products and processes.
Green chemistry synthetic routes of N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide methanesulfonate involve the use of reagents and conditions that are less hazardous and more environmentally friendly than conventional methods.
One example of a green chemistry synthetic route of N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide methanesulfonate involves the use of a process called "Palladium-Catalyzed Cross-Coupling Reactions.
" This process involves the reaction of a suitably substituted aryl halide with a suitably substituted pyridine, in the presence of a palladium catalyst.
The resulting product is then treated with a base to form the desired product.
Another example of a green chemistry synthetic route involves the use of a process called "Organocatalytic Asymmetric Condensation.
" This process involves the reaction of a suitably substituted amine with a suitably substituted carbonyl compound, in the presence of an organocatalyst.
The resulting product is then treated with a base to form the desired product.
Biotechnology Synthetic Routes
Biotechnology is a field that involves the use of living organisms or their products to make useful