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    Home > Active Ingredient News > Drugs Articles > The Synthetic Routes of Desfluoro EzetiMibe

    The Synthetic Routes of Desfluoro EzetiMibe

    • Last Update: 2023-04-26
    • Source: Internet
    • Author: User
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    Desfluoro EzetiMibe is an anti-tuberculosis drug that is used to treat tuberculosis infections.
    It is a second-line anti-TB drug, which means that it is used when other anti-TB drugs have failed to work.
    The drug is a synthetic compound that is made in the laboratory, rather than being derived from natural sources.
    The synthetic route of Desfluoro EzetiMibe is a complex and multistep process that involves several chemical reactions.


    The synthetic route of Desfluoro EzetiMibe starts with the synthesis of a precursor compound called 2-chloro-N-(2,6-difluoro-3-oxo-1,4-oxazepin-9-yl)acetamide.
    This compound is synthesized by reacting 2,6-difluoro-3-oxo-1,4-oxazepine with acetaldehyde in the presence of a catalyst.
    The reaction produces the desired precursor compound, which is then transformed into Desfluoro EzetiMibe through a series of chemical reactions.


    The next step in the synthetic route of Desfluoro EzetiMibe is the oxidation of the precursor compound to produce the parent compound, called 2-chloro-N-(2,6-difluoro-3-oxo-1,4-oxazepin-9-yl)acetamide.
    This is achieved by treating the precursor compound with ozone and hydrochloric acid.
    The resulting compound is then reduced to produce the desired parent compound.


    The final step in the synthetic route of Desfluoro EzetiMibe is the esterification of the parent compound to produce the final drug.
    This is achieved by treating the parent compound with an acid chloride in the presence of a catalyst.
    The resulting compound is then purified and dried to produce the final drug.


    The synthetic route of Desfluoro EzetiMibe is a complex and multistep process that requires specialized equipment and expertise.
    The production of the drug involves several chemical reactions, including oxidation, reduction, and esterification.
    The drug is synthesized in the laboratory, rather than being derived from natural sources, and is therefore a synthetic compound.
    The synthetic route of Desfluoro EzetiMibe is an important process in the production of this anti-TB drug, which is used to treat tuberculosis infections.


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