The Synthetic Routes of Calcium (βS,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2)

The Synthetic Routes of Calcium (βS,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2)

In the world of chemistry, the synthesis of new molecules is a constant pursuit.
The creation of novel compounds with unique properties is of great importance in various fields, such as medicine, materials science, and agriculture.
One such compound is Calcium (βS,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2), a synthetic molecule with potential medical applications.
In this article, we will explore the various synthetic routes that have been developed to create this compound.

The Synthesis of Calcium (βS,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2)

Calcium (βS,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2) is a complex molecule composed of various functional groups, including esters, amides, and aromatic rings.
The synthesis of this compound involves several steps, each of which requires careful planning and execution.

One of the most common methods of synthesizing this compound involves a sequence of reactions that include the following steps:

1. Condensation of 4-fluorophenyl acetate with β-phenyl-δ-butyric acid
2. Condensation of the product from step 1 with 1-methylethyl amide
3. Condensation of the product from step 2 with 3-phenyl pyruvate
4. Condensation of the product from step 3 with phenyl amino carbonyl chloride
5. Condensation of the product from step 4 with heptanoic acid

Another route to the synthesis of Calcium (βS,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2) involves the use of a sequence of reactions that include the following steps:

1. Condensation of 4-fluorophenyl chloride with δ-butyraldehyde in the presence of a Lewis acid catalyst, such as aluminum chloride
2. Condensation of the product from step 1 with β-phenyl amino alcohol
3. Condensation of the product from step 2 with 1-methylethyl isocyanate
4. Condensation of the product from step 3 with 3-phenyl pyruvate
5. Condensation of the product from step 4 with phenyl amino carbonyl chloride
6. Condensation of the product from step 5 with heptanoic acid

Yet another route to the synthesis of Calcium (βS,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2) involves the use of a sequence of reactions that include the following steps:

1. Condensation of 4-fluorophenyl salicylate with δ-