The Synthetic Routes of 8-BROMO-2-METHYL-QUINOLINE

8-BROMO-2-METHYL-QUINOLINE, commonly referred to as 8-bromo-2-methyl-quinoline, is a synthetic compound that belongs to the class of quinolines.
Quinolines are a group of chemical compounds that contain a six-membered ring with two nitrogen atoms.
8-Bromo-2-methyl-quinoline is an important synthetic intermediate that is used in the production of various chemicals, pharmaceuticals, and agrochemicals.

One of the most commonly used synthetic routes for the production of 8-bromo-2-methyl-quinoline involves the reaction of 2-methylquinoline with chloroform in the presence of a Lewis acid catalyst, such as boron trifluoride or aluminum trichloride.
The reaction typically takes place in a solvent, such as dichloromethane or chloroform, and the product is typically purified by recrystallization or chromatography.

Another synthetic route for the production of 8-bromo-2-methyl-quinoline involves the reaction of 2-methyl-6-bromo-quinoline with methyl iodide in the presence of a base, such as sodium hydroxide or potassium hydroxide.
The reaction typically takes place in a solvent, such as water or dioxane, and the product is typically purified by recrystallization or chromatography.

8-Bromo-2-methyl-quinoline can also be synthesized by other synthetic routes, such as the reaction of 2-methyl-5-bromo-quinoxaline with 2-bromo-1-methyl-2-propanol in the presence of a base, such as sodium hydroxide or potassium hydroxide.
The reaction typically takes place in a solvent, such as water or dioxane, and the product is typically purified by recrystallization or chromatography.

Once synthesized, 8-bromo-2-methyl-quinoline can be further transformed into other chemicals, such as 8-bromo-2-methyl-quinoline derivatives, which are used in the production of pesticides, herbicides, and other agrochemicals.
8-bromo-2-methyl-quinoline derivatives can also be used as pharmaceuticals, intermediates in the production of pharmaceuticals, or as research reagents.

In conclusion, 8-bromo-2-methyl-quinoline is an important synthetic compound that is widely used in the production of various chemicals, pharmaceuticals, and agrochemicals.
There are several synthetic routes for the production of 8-bromo-2-methyl