-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
The synthetic route to (6-chloro-pyridazin-3-yl)-piperidin-4-ylmethylamine hydrochloride, also known as compound C, is a complex and multi-step process that involves several different chemical reactions.
The synthesis of this compound is of great interest in the chemical industry due to its potential use as a pharmaceutical agent.
The synthesis of compound C typically begins with the synthesis of an intermediate compound, which is then transformed into the final product through a series of chemical reactions.
The following is a detailed description of the synthetic route to compound C:
Step 1: Synthesis of intermediate compound
The synthesis of the intermediate compound begins with the reaction of 4-chloro-6-aminopyrimidine with N-methylpiperazine in the presence of a solvent such as toluene.
This reaction is followed by the addition of an excess of hydrazine, which leads to the formation of the intermediate compound.
Step 2: Condensation reaction
The intermediate compound is then subjected to a condensation reaction, typically using a reagent such as hydrochloric acid, to form the final product.
This reaction involves the removal of the amine group from the intermediate compound, followed by the addition of the chlorine atom from the hydrochloric acid to form the final product.
Step 3: Purification and isolation
Once the final product has been synthesized, it must be purified and isolated from any other components that may be present.
This is typically done using a series of chromatographic techniques, such as column chromatography or high-performance liquid chromatography (HPLC).
The purification and isolation step is crucial in the synthesis of compound C, as it ensures that the final product is of a high purity and is free from any impurities that may interfere with its activity as a pharmaceutical agent.
In conclusion, the synthetic route to (6-chloro-pyridazin-3-yl)-piperidin-4-ylmethylamine hydrochloride involves several different chemical reactions, including the synthesis of an intermediate compound, a condensation reaction, and purification and isolation of the final product.
The synthesis of compound C is a complex and challenging process, but it is of great importance in the chemical industry due to its potential use as a pharmaceutical agent.