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5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxamide is an important compound in the field of pharmaceuticals and has a wide range of applications in the treatment of various diseases.
The compound can be synthesized through several synthetic routes, each with its own advantages and disadvantages.
In this article, we will discuss some of the most commonly used synthetic routes for the synthesis of 5-acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxamide.
- One of the most commonly used methods for synthesizing 5-acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxamide involves the use of a condensation reaction between N-(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethylamine and 5-acetyl-1H-pyrazole-3-carboxylic acid.
This method involves the use of readily available reagents and simple reaction conditions, making it a popular choice for synthesizing this compound. - Another commonly used synthetic route involves the use of a coupling reaction between N-(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethylamine and 5-acetyl-1H-pyrazole-3-sulphonic acid.
This method involves the use of sulfuric acid as a catalyst, which can be both expensive and hazardous to handle. - A third synthetic route involves the use of an alkylation reaction between N-(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethylamine and 5-acetyl-1H-pyrazole-3-iodide.
This method involves the use of iodine as a reagent, which can be both expensive and hazardous to handle.
In conclusion, there are several synthetic routes available for the synthesis of 5-acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxamide, each with its own advantages and disadvantages.
The choice of synthetic route will depend on the availability of reagents, the complexity of the reaction conditions, and the cost and safety considerations of the reagents used.
