The Synthetic Routes of 4-Pyridazinecarbonitrile,3-amino-(9CI)

4-Pyridazinecarbonitrile,3-amino-(9CI) is a compound that is widely used in various chemical reactions and synthesis methods.
Due to its unique structure and chemical properties, it has a wide range of applications in the pharmaceutical, agrochemical, and other industries.
In this article, we will discuss the synthetic routes of 4-Pyridazinecarbonitrile,3-amino-(9CI) and the methods used in its synthesis.

One of the most common methods for synthesizing 4-Pyridazinecarbonitrile,3-amino-(9CI) is through the nitrilation of 3-pyridazinecarboxylic acid with nitric acid.
This reaction is carried out in the presence of a solvent, such as water or dimethylformamide, and is typically exothermic, requiring careful temperature control.
The product is then recovered from the reaction mixture by precipitation, filtration, or other methods.

Another method for synthesizing 4-Pyridazinecarbonitrile,3-amino-(9CI) is through the oxidation of 3-pyridazinecarboxylic acid with hydrogen peroxide.
This reaction is also carried out in the presence of a solvent and typically involves heating the reaction mixture to accelerate the reaction.
The product may be recovered from the reaction mixture by precipitation, filtration, or other methods.

A third method for synthesizing 4-Pyridazinecarbonitrile,3-amino-(9CI) is through the reduction of 3-pyridazinecarboxaldehyde with lithium aluminum hydride (LiAlH4) in the presence of a solvent, such as ether or tetrahydrofuran.
This reaction is typically carried out at a lower temperature and requires careful handling of the reagents to avoid formation of unwanted byproducts.
The product is then recovered from the reaction mixture by precipitation, filtration, or other methods.

In addition to the above methods, 4-Pyridazinecarbonitrile,3-amino-(9CI) may also be synthesized through other routes, such as the condensation of 3-pyridazinecarboxylic acid with ammonia, the reduction of 3-pyridazinecarboxylic acid with hydrogen in the presence of a catalyst, or the nitration of 3-pyridazinecarboxylic acid with nitric acid in the presence of a solvent.

Overall, the synthetic routes of 4-Pyridazinecarbonitrile,3-amino-(9CI) are diverse and can vary depending on the specific application and desired properties of the final product.
Regardless of the method used, the synthesis of 4-Pyridazinecarbonitrile,3-amino-(9CI) requires careful attention to the reaction conditions and handling of the reagents to ensure the production of a high-quality product.