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    Home > Medical News > Medical World News > The Synthetic Routes of 4-IODOISOQUINOLINE

    The Synthetic Routes of 4-IODOISOQUINOLINE

    • Last Update: 2023-05-10
    • Source: Internet
    • Author: User
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    4-Iodoisoquoline is a type of organic compound that is widely used in the chemical industry.
    It is a white or yellowish-white solid that is soluble in water and organic solvents.
    The compound is used as a reagent in various chemical reactions and is also used as a synthetic intermediate for the production of other chemicals.


    One of the most common methods of synthesizing 4-iodoisoquoline is through the reaction of isatin with chloroform in the presence of a base, such as sodium hydroxide.
    Isatin is a derivative of catechol, which is a naturally occurring compound found in various plants and animals.
    The reaction between isatin and chloroform in the presence of sodium hydroxide results in the formation of 4-iodoisoquoline, with the liberation of hydrochloric acid as a byproduct.


    Another method of synthesizing 4-iodoisoquoline involves the reaction of 4-nitroisoquinoline with potassium iodide in the presence of a solvent, such as ethanol.
    The reaction results in the substitution of the nitro group in 4-nitroisoquinoline with the iodine atom, resulting in the formation of 4-iodoisoquoline.


    4-Iodoisoquoline can also be synthesized through the reaction of catechol with chloroform in the presence of a base, such as sodium hydroxide.
    The reaction results in the formation of 4-iodoisoquoline, with the liberation of hydrochloric acid as a byproduct.


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