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4-Chloro-3-iodo-pyridin-2-ylimine is an important intermediate in the synthesis of various chemicals and pharmaceuticals.
This compound has a wide range of applications in the chemical industry, and its synthetic routes have been extensively studied and developed over the years.
One of the most commonly used methods for the synthesis of 4-chloro-3-iodo-pyridin-2-ylimine is through the reaction of 2-chloro-4-iodo-pyridine with 2-aminopyridine in the presence of a solvent such as dichloromethane or chloroform.
This reaction is typically carried out at a temperature of around 0°C, and the resulting product is then purified through a series of chromatography steps before being isolated.
Another synthetic route to 4-chloro-3-iodo-pyridin-2-ylimine involves the reaction of iodine with 3-chloro-pyridine-2-amine in the presence of a solvent such as toluene or xylene.
This reaction is typically carried out at a temperature of around 100°C, and the resulting product is then purified through a series of chromatography steps before being isolated.
A third synthetic route to 4-chloro-3-iodo-pyridin-2-ylimine involves the reaction of 2-chloro-4-iodo-pyridine with 2-aminopyridine in the presence of a solvent such as dimethyl formamide.
This reaction is typically carried out at a temperature of around 150°C and the resulting product is then purified through a series of chromatography steps before being isolated.
The choice of synthetic route for 4-chloro-3-iodo-pyridin-2-ylimine depends on several factors, such as the availability of reagents, the desired yield and purity of the product, and the cost and safety considerations associated with the process.
In conclusion, 4-chloro-3-iodo-pyridin-2-ylimine is an important intermediate in the synthesis of various chemicals and pharmaceuticals and its synthetic routes are extensively studied and developed over the years.
Synthetic routes to 4-chloro-3-iodo-pyridin-2-ylimine include reaction of 2-chloro-4-iodo-pyridine with 2-aminopyridine, iodine with 3-chloro-pyridine-2-amine, and 2-chloro-4-iodo-pyridine with 2-aminopyridine in the presence of different solvents.
The choice of synthetic route depends on several factors such as the availability of reagents, the desired yield and purity of the product, and the cost and safety considerations associated with the process.
