The Synthetic Routes of 4,6-Dichloro-3-methyl-isoxazolo[5,4-d]pyrimidine

4,6-Dichloro-3-methyl-isoxazolo[5,4-d]pyrimidine is an important synthetic intermediate in the chemical industry, with a wide range of applications in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
This compound can be synthesized through several different routes, each with its own advantages and disadvantages.

One of the most common methods for synthesizing 4,6-dichloro-3-methyl-isoxazolo[5,4-d]pyrimidine involves the reaction of 3-methyl-isoxazolo[5,4-d]pyrimidine-2,4-dione with chloroform.
This reaction is carried out in the presence of a strong acid catalyst, such as sulfuric acid, and results in the formation of the desired compound.

Another synthesis route for 4,6-dichloro-3-methyl-isoxazolo[5,4-d]pyrimidine involves the reaction of 3-methyl-isoxazole-4,6-dione with phosphorus trichloride in the presence of a solvent, such as dichloromethane.
This reaction is typically carried out under anhydrous conditions and results in the formation of the desired compound.

Yet another synthesis route for 4,6-dichloro-3-methyl-isoxazolo[5,4-d]pyrimidine involves the reaction of 3-methyl-isoxazole-4-carboxylic acid with potassium permanganate in the presence of a solvent, such as ethanol.
This reaction is typically carried out under acidic conditions and results in the formation of the desired compound.

Overall, the synthesis of 4,6-dichloro-3-methyl-isoxazolo[5,4-d]pyrimidine is a well-established process in the chemical industry, with several different synthesis routes available depending on the specific requirements of the application.
The compound is an important intermediate in the production of a wide range of chemicals and pharmaceuticals, and its synthesis is a critical step in the manufacturing process for these products.