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4,5-Dimethylpyridazine-3,6-diol is an organic compound that is widely used in various industries, including the chemical, pharmaceutical, and cosmetic industries.
The compound is synthesized through several routes, both natural and synthetic.
This article will discuss the synthetic routes of 4,5-Dimethylpyridazine-3,6-diol.
The most common method of synthesizing 4,5-Dimethylpyridazine-3,6-diol is through the reaction of 4-methoxy-6-nitroquinoline with 3,5-dimethylpyrazine-2-carboxaldehyde.
In this method, the aldehyde is first converted into an N-methylnitrosoamide by reaction with methyl iodide and hydroxylamine.
This intermediate is then converted into the desired product through the reaction with 2,3-dimethyl-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-9-one.
Another method of synthesizing 4,5-Dimethylpyridazine-3,6-diol is through the reaction of 4-methoxy-6-nitroquinoline with 3,5-dimethyl-2-(methylamino)pyrazine-4-carboxaldehyde.
This method involves converting the carboxaldehyde into an N-methylnitrosoamide using methyl iodide and hydroxylamine, followed by reaction with 4-methoxy-6-nitroquinoline to form the desired product.
A third method of synthesizing 4,5-Dimethylpyridazine-3,6-diol is through the reaction of 4-methoxy-6-nitroquinoline with 3,5-dimethyl-4-(methylamino)-2-oxazolidinone.
This method involves the conversion of the oxazolidinone into an N-methylnitrosoamide using methyl iodide and hydroxylamine, followed by reaction with 4-methoxy-6-nitroquinoline to form the desired product.
In addition to these methods, there are several other synthetic routes to 4,5-Dimethylpyridazine-3,6-diol.
These include the synthesis of the compound from 4-methoxy-6-nitrobenzaldehyde, 3,5-dimethyl-2-oxazolidinone, and 2,3-dimethyl-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-9-one.
Another route involves the synthesis of the compound from 4-methoxy-6-nitroquinoline, 3,5-dimethyl-4-(methylamino)-2-oxazolidinone, and 2,3-dimethyl-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-9-one.
The synthetic routes to 4,5-Dimethylpyridazine-3,6-diol vary in terms of the specific reagents used, the number of steps involved, and the overall yield of the desired product.
However, all of these routes involve the conversion of the starting materials into the desired product through a series of chemical reactions.
The synthesis of 4,5-Dimethylpyridazine-3,6-diol has several applications in the chemical industry, particularly in the development of new drugs and other chemical products.
The compound has been used as an intermediate in the synthesis of a number of pharmaceuticals, including ant