The Synthetic Routes of (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N,

The synthetic routes of (3R,4R,5S)-4-N-Acetyl(1,1-dimethylethyl)amino-5-N- (4,5-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl)amide (compound 1) are of great importance in the synthesis of this compound, which has been widely studied for its potential as an anti-inflammatory and anti-allergic agent.
The synthetic routes of this compound can be broadly classified into two categories: traditional synthetic routes and contemporary synthetic routes.

Traditional Synthetic Routes
The traditional synthetic routes for the synthesis of compound 1 have been based on various chemical reactions, including condensation reactions, substitution reactions, and reduction reactions.
Some of the commonly used traditional reactions for the synthesis of this compound are:

1. Condensation reactions: Condensation reactions, such as the Wittig reaction, the Horner-Emmons reaction, and the Barton-McCombie reaction, have been widely used for the synthesis of compound 1.
   These reactions involve the formation of a new carbon-carbon bond through the condensation of two different reactants.
   
2. Substitution reactions: Substitution reactions, such as the Hofmann reaction and the Stereogenic Mesomeric Effect, have also been used for the synthesis of compound 1.
   These reactions involve the substitution of one functional group with another functional group, which can result in the formation of new carbon-carbon bonds.
   
3. Reduction reactions: Reduction reactions, such as the Birch reduction and the Wolff-Kishner reduction, have been used for the synthesis of compound 1.
   These reactions involve the reduction of a carbonyl group to a primary or secondary carbon atom.
   

Contemporary Synthetic Routes
The contemporary synthetic routes for the synthesis of compound 1 have been based on various modern chemical reactions, including organic reactions, such as alkylation reactions, acylation reactions, and alkynylation reactions, and inorganic reactions, such as hydride reduction and hydroboration reduction.
Some of the commonly used contemporary reactions for the synthesis of this compound are:

1. Organic reactions: Organic reactions, such as the Ullmann reaction, the Appel reaction, and the Sonogashira reaction, have been widely used for the synthesis of compound 1.
   These reactions involve the addition of two different reactants to form a new carbon-carbon bond.
   
2. Inorganic reactions: Inorganic reactions, such as hydride reduction and hydroboration reduction, have also been used for the synthesis of compound 1.
   These reactions involve the reduction of a functional group using a reducing agent, such as lithium aluminum hydride or sodium borohydride.
   

Advantages of the Contemporary Synthetic Routes
The contemporary synthetic routes for the synthesis of compound 1 have several advantages over the traditional synthetic routes.
These advantages include:

1. Increased Synthetic Efficiency: The contemporary synthetic routes for the synthesis of compound 1 are generally more efficient than the traditional synthetic routes.
   This is because the contemporary reactions are more predictable and have a higher yield, which can result in a more efficient synthesis process.
   
2. Greater Selectivity: The contemporary synthetic routes for the synthesis of compound 1 can offer greater selectivity than the traditional synthetic routes.
   This is because the contemporary reactions are more controllable, which can result in a higher degree of selectivity.
   
3. Reduced Costs: The contemporary synthetic routes for the synthesis of compound 1 can result in reduced costs compared to the traditional synthetic routes.
   This is because the contemporary reactions