The Synthetic Routes of 3-Pyridazinecarboxylicacid,1,6-dihydro-1-methyl-6-oxo-(6CI)

3-Pyridazinecarboxylicacid,1,6-dihydro-1-methyl-6-oxo-(6CI) is a compound that has been widely studied and used in various chemical reactions and synthesis.
It has also been found to have potential medical applications.
The synthetic routes for this compound have been widely explored and continue to be an area of ongoing research in the chemical industry.

One of the most common synthetic routes for 3-Pyridazinecarboxylicacid,1,6-dihydro-1-methyl-6-oxo-(6CI) involves the reaction of 3-aminopyridazine with acryloyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride.
This reaction results in the formation of a polar amide intermediate, which undergoes dehydration to form the desired product.

Another synthetic route involves the reaction of 3-aminopyridazine with methyl 2-chloroacetate in the presence of a base such as sodium hydroxide.
This reaction results in the formation of the corresponding methyl ester, which can then be dehydrogenated to form the desired product.

In recent years, there has been increasing interest in the use of enzymatic methods for the synthesis of 3-Pyridazinecarboxylicacid,1,6-dihydro-1-methyl-6-oxo-(6CI).
This involves the use of enzymes such as decarboxylases or deaminases to convert the starting materials into the desired product.
This method has the advantage of being more environmentally friendly, as it avoids the use of toxic chemicals, and can also be more efficient than traditional synthetic methods.

The choice of synthetic route for 3-Pyridazinecarboxylicacid,1,6-dihydro-1-methyl-6-oxo-(6CI) depends on various factors such as the availability of starting materials, the desired yield and purity of the product, and the cost and efficiency of the synthetic method.

In conclusion, the synthetic routes for 3-Pyridazinecarboxylicacid,1,6-dihydro-1-methyl-6-oxo-(6CI) have been widely explored and continue to be an area of ongoing research in the chemical industry.
The various synthetic methods available, including enzymatic methods, offer a range of options for the production of this compound.
The choice of synthetic route depends on various factors such as the availability of starting materials, the desired yield and purity of the product, and the cost and efficiency of the synthetic method.