-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
3-Pyridazinamine, which is also known as 2-amino-3-imidazoline, is a organic compound that has a wide range of applications in various industries.
It is commonly used as an intermediate in the production of various pharmaceuticals, dyes, and other chemicals.
The synthetic routes for 3-pyridazinamine can vary depending on the desired product and the starting materials available.
One of the most common methods for synthesizing 3-pyridazinamine involves the reduction of 2-imidazoline, which is then followed by nitration to introduce the nitro group.
The reaction can be carried out in the presence of a reducing agent such as lithium aluminum hydride (LiAlH4) or hydrogen in the presence of a catalyst such as palladium on barium sulfate.
The resulting 3-pyridazinamine can then be purified and used as a starting material for further reactions.
Another synthetic route for 3-pyridazinamine involves the reaction of aniline with acetic anhydride in the presence of a strong base such as sodium hydroxide.
The reaction produces 3-pyridazinamine, which can then be separated and purified from the reaction mixture.
Another approach is the synthesis of 3-pyridazinamine through the oxidation of 2-aminopyridine using oxidizing agents such as potassium permanganate or sodium periodate.
The oxidation reaction can be carried out in the presence of a solvent such as water or a mixture of water and an organic solvent.
The resulting 3-pyridazinamine can then be purified and used as a starting material for further reactions.
In addition to the above-mentioned routes, 3-pyridazinamine can also be synthesized through the nitration of 2-aminopyridine, the hydrochlorination of 2-aminopyridine, and the deaminization of N-methylpyrrole.
In the chemical industry, 3-pyridazinamine is used as an intermediate in the production of various pharmaceuticals, dyes, and other chemicals.
It is also used in the production of certain herbicides and pesticides.
There are several advantages of synthesizing 3-pyridazinamine using the above-mentioned methods.
Firstly, these methods are relatively simple and can be carried out using easily available starting materials.
Secondly, these methods do not require the use of expensive and hazardous reagents.
Finally, the products obtained from these reactions can be further used as starting materials for the synthesis of other compounds.
Overall, the synthetic routes of 3-pyridazinamine are varied and can be tailored to specific applications in the chemical industry.
The compound is widely used as an intermediate in the production of various chemicals and pharmaceuticals, and its synthesis can be accomplished using relatively simple and inexpensive methods.