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    Home > Medical News > Medical World News > The Synthetic Routes of 3-CHLOROTHIOPHENE-2-CARBALDEHYDE

    The Synthetic Routes of 3-CHLOROTHIOPHENE-2-CARBALDEHYDE

    • Last Update: 2023-05-09
    • Source: Internet
    • Author: User
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    3-Chlorothiophene-2-carbaldehyde is a synthetic compound that is widely used in the chemical industry.
    It is a colorless liquid with a strong, unpleasant odor, and it is highly soluble in water.
    This compound is used as a building block for the synthesis of a variety of other chemicals, and it is also used as a catalyst in certain chemical reactions.


    One of the most common synthetic routes to 3-chlorothiophene-2-carbaldehyde involves the reaction of 2-nitrobenzaldehyde with chloroform in the presence of a Lewis acid catalyst, such as aluminum chloride.
    This reaction results in the formation of the desired compound, as well as a byproduct of nitrobenzene.


    Another synthetic route to 3-chlorothiophene-2-carbaldehyde involves the reaction of phenyl isocyanate with thiophenol in the presence of a metal catalyst, such as tin(II) chloride.
    This reaction results in the formation of the desired compound, as well as a byproduct of diphenyl carbonate.


    The compound can also be synthesized by the reduction of 3-chlorothiophene-2-carboxaldehyde using hydrogen gas in the presence of a metal catalyst, such as palladium on barium sulfate.
    This reaction results in the formation of the desired compound, as well as a byproduct of hydrogen chloride.


    3-chlorothiophene-2-carbaldehyde is a highly reactive compound, and it is often used as a building block for the synthesis of other chemicals.
    For example, it can be converted into 3-chlorothiophene-2-carboxylic acid, which is used as a flavoring agent in food products, or into 3-chlorothiophene-2-carboxylic acid, which is used as a catalyst in the production of polyester fibers.


    The compound can also be used as a catalyst in certain chemical reactions.
    For example, it can be used to catalyze the esterification reaction between acetic acid and ethanol, resulting in the formation of ethyl acetate.


    Overall, 3-chlorothiophene-2-carbaldehyde is an important synthetic compound in the chemical industry, and it is widely used as a building block for the synthesis of other chemicals and as a catalyst in certain chemical reactions.
    Its synthetic routes include the reaction of 2-nitrobenzaldehyde with chloroform in the presence of a Lewis acid catalyst, such as aluminum chloride, the reaction of phenyl isocyanate with thiophenol in the presence of a metal catalyst, such as tin(II) chloride, or the reduction of 3-chlorothiophene-2-carboxaldehyde using hydrogen gas in the presence of a metal catalyst, such as palladium on barium sulfate.
    It is highly reactive compound and it is often used as a building block for the synthesis of other chemicals and as a catalyst in certain chemical reactions.


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