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The Synthetic Routes of 3-chloro-7H-pyrrolo[2,3-c]pyridazine

 Last Update: 2023-05-17
 Source: Internet
 Author: User

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3-chloro-7H-pyrrolo[2,3-c]pyridazine is a compound that has been widely studied and used in various industries, particularly in the field of pharmaceuticals and agrochemicals.
The compound has unique properties that make it suitable for various applications, and its synthesis has been a topic of interest in the chemical industry.
In this article, we will discuss some of the synthetic routes that are commonly used to synthesize 3-chloro-7H-pyrrolo[2,3-c]pyridazine.

Hydrochlorination of 7H-pyrrolo[2,3-c]pyridazine
The first step in the synthesis of 3-chloro-7H-pyrrolo[2,3-c]pyridazine involves the hydrochlorination of 7H-pyrrolo[2,3-c]pyridazine.
This reaction involves the treatment of 7H-pyrrolo[2,3-c]pyridazine with hydrochloric acid, which leads to the substitution of one of the nitrogens with a chlorine atom.
The reaction is typically carried out in the presence of a solvent, such as dichloromethane, and a catalyst, such as ferric chloride.
The reaction is exothermic, and care must be taken to avoid excessive heating.
The product can be isol

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