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    Home > Medical News > Medical World News > The Synthetic Routes of 3-(2-Bromoethyl)oxazolo[4,5-b]pyridin-2(3H)-one

    The Synthetic Routes of 3-(2-Bromoethyl)oxazolo[4,5-b]pyridin-2(3H)-one

    • Last Update: 2023-05-04
    • Source: Internet
    • Author: User
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    3-(2-Bromoethyl)oxazolo[4,5-b]pyridin-2(3H)-one is an important chemical compound used in various industries, including pharmaceuticals and agrochemicals.
    The synthesis of this compound involves several steps, and there are several synthetic routes available in the chemical industry.


    One of the most commonly used synthetic routes involves the reaction of 2-bromoethyl oxazole with ortho-dibrompyridine in the presence of a solvent such as acetonitrile or DMF.
    This reaction is often carried out at a temperature of 100-120 degrees Celsius, and the resulting product is then purified using methods such as recrystallization or column chromatography.


    Another synthetic route involves the reaction of 2-bromoethyl oxazole with pyridine-2,3-dibromide in the presence of a solvent such as DMSO or NMP.
    This reaction is often carried out at a temperature of 100-120 degrees Celsius, and the resulting product is then purified using methods such as recrystallization or column chromatography.


    A third synthetic route involves the reaction of 2-bromoethyl oxazole with 2,3-dibromopyridine in the presence of a solvent such as DMSO or NMP.
    This reaction is often carried out at a temperature of 100-120 degrees Celsius, and the resulting product is then purified using methods such as recrystallization or column chromatography.


    The choice of synthetic route depends on various factors, such as the availability of reagents, the desired yield, and the purity of the final product.
    Additionally, the cost of the synthesis is also an important consideration for large-scale industrial production.


    Once synthesized, 3-(2-bromoethyl)oxazolo[4,5-b]pyridin-2(3H)-one can be used in various applications in the pharmaceutical and agrochemical industries.
    For example, it can be used as an intermediate in the synthesis of anti-inflammatory drugs, antifungal agents, and herbicides.


    In conclusion, 3-(2-bromoethyl)oxazolo[4,5-b]pyridin-2(3H)-one is an important chemical compound used in various industries, and there are several synthetic routes available for its synthesis.
    The choice of synthetic route depends on various factors, such as the availability of reagents, the desired yield, and the cost of production.
    Once synthesized, this compound can be used in various applications in the pharmaceutical and agrochemical industries.


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