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2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt is a compound that has gained significant interest in the chemical industry due to its unique properties and potential applications.
The compound has been extensively studied, and several synthetic routes have been developed to produce it.
In this article, we will discuss some of the most commonly used synthetic routes for 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt.
Route 1: Via Cyclization of N-(2-Amino-1-methylcyclohexyl)methylamine
One of the most common synthetic routes for 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt involves the cyclization of N-(2-amino-1-methylcyclohexyl)methylamine.
To synthesize the compound, N-(2-amino-1-methylcyclohexyl)methylamine is treated with a strong acid such as hydrochloric acid, which causes the compound to undergo cyclization, leading to the formation of 2-(Aminomethyl)cyclobutyl]methanamine.
The resulting compound is then treated with sodium hydroxide to convert it to 2-(Aminomethyl)cyclobutyl]methanamine hydrochloride.
Finally, the platinum salt is introduced into the solution, and the reaction is carried out at high temperature for several hours.
The final product is then extracted, purified, and dried to obtain pure 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt.
Route 2: Via Hydrolysis of N-(2-(Aminomethyl)cyclobutyl)methylamine
Another synthetic route for 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt involves the hydrolysis of N-(2-(Aminomethyl)cyclobutyl)methylamine.
To synthesize the compound, N-(2-(Aminomethyl)cyclobutyl)methylamine is treated with a strong acid such as hydrochloric acid, which causes the compound to undergo hydrolysis, leading to the formation of 2-(Aminomethyl)cyclobutylamine.
The resulting compound is then treated with sodium hydroxide to convert it to 2-(Aminomethyl)cyclobutylamine hydrochloride.
Finally, the platinum salt is introduced into the solution, and the reaction is carried out at high temperature for several hours.
The final product is then extracted, purified, and dried to obtain pure 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt.
Route 3: Via Reduction of N-(2-Amino-1-(2-hydroxyethyl)cyclohexyl)methylamine
A third synthetic route for 2-(Aminomethyl)cyclobutyl]methanamine 2-hydroxypropanoic acid platinum salt involves the reduction of N-(2-amino-1-(2-hydroxyethyl)cyclohexyl)methylamine.
To synthesize the compound, N-(2-amino-1-(2-hydroxyethyl)cyclohexyl)methylamine is treated with a reducing agent such as lithium aluminum hydride, which causes the compound to undergo reduction, leading to the formation of N-(2-amino-1-(2-hydroxyethyl)cyclohexyl)methanamine.
The resulting compound is then treated with sodium hydroxide to convert it to N-(2-amino-1-(2-hydroxyeth