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    Home > Medical News > Medical World News > The Synthetic Routes of 2,6-Dichloro-N-(1-methylethyl)-4-pyrimidinemethanamine

    The Synthetic Routes of 2,6-Dichloro-N-(1-methylethyl)-4-pyrimidinemethanamine

    • Last Update: 2023-05-04
    • Source: Internet
    • Author: User
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    2,6-Dichloro-N-(1-methylethyl)-4-pyrimidinemethanamine is an organic compound that is commonly used in the chemical industry.
    It is a colorless liquid with a distinctive odor, and it is soluble in water.
    The molecule has a pyridine ring attached to a pyrimidine ring, which is substituted with two chlorine atoms.
    This molecule is used as a precursor to a variety of other chemicals, and it can be synthesized using several different methods.


    One synthetic route to 2,6-dichloro-N-(1-methylethyl)-4-pyrimidinemethanamine involves the reaction of 4-chloro-2,6-dimethylpyrimidine with 1-methylethylamine.
    This reaction can be carried out using typical conditions for nucleophilic substitution reactions, such as the use of a strong base, such as sodium hydroxide, and a polar solvent, such as water.
    The resulting product can then be purified by crystallization or by chromatography.


    Another synthetic route to 2,6-dichloro-N-(1-methylethyl)-4-pyrimidinemethanamine involves the reaction of 2,6-dichloropyrimidine-4-amine with 1-methylethyl chloride.
    This reaction can be carried out using typical conditions for electrophilic substitution reactions, such as the use of a strong acid, such as sulfuric acid, and a polar solvent, such as water.
    The resulting product can then be purified by crystallization or by chromatography.


    A third synthetic route to 2,6-dichloro-N-(1-methylethyl)-4-pyrimidinemethanamine involves the reaction of 4-chloro-2,6-dimethylpyrimidine with N-methylethylamine.
    This reaction can be carried out using typical conditions for nucleophilic substitution reactions, such as the use of a strong base, such as sodium hydroxide, and a polar solvent, such as water.
    The resulting product can then be purified by crystallization or by chromatography.


    Overall, there are several synthetic routes to 2,6-dichloro-N-(1-methylethyl)-4-pyrimidinemethanamine, and the choice of route will depend on the specific needs of the chemical industry.
    The compound is widely used as a building block for the synthesis of other chemicals, and it is a valuable intermediate in the production of a variety of chemical products.


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