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    Home > Active Ingredient News > Drugs Articles > The Synthetic Routes of 2-((2S,3S,4R,5R)-5-((S)-2,3-Bis(tert-butyldimethylsilyloxy)propyl)-4-methoxy-3-(tosylmethyl)tetrahydrofuran-2-yl)acetaldehyde

    The Synthetic Routes of 2-((2S,3S,4R,5R)-5-((S)-2,3-Bis(tert-butyldimethylsilyloxy)propyl)-4-methoxy-3-(tosylmethyl)tetrahydrofuran-2-yl)acetaldehyde

    • Last Update: 2023-05-10
    • Source: Internet
    • Author: User
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    2-((2S,3S,4R,5R)-5-((S)-2,3-Bis(tert-butyldimethylsilyloxy)propyl)-4-methoxy-3-(tosylmethyl)tetrahydrofuran-2-yl)acetaldehyde, also known as Xxxx, is an organic compound that is commonly used in the chemical industry.
    It is a synthetic intermediate that is used in the production of various chemicals, pharmaceuticals, and other products.
    The compound is synthesized through a series of chemical reactions that involve several steps and various reagents.
    The synthetic routes of Xxxx are highly complex and require a good understanding of organic chemistry and the use of specialized equipment and techniques.


    One of the most common synthetic routes for Xxxx involves the following steps:


    1. Preparation of the starting material: The synthesis of Xxxx begins with the preparation of the starting material, which is a compound known as (2S,3S)-2,3-Bis(tert-butyldimethylsilyloxy)propanamide.
      This compound is synthesized through a series of chemical reactions that involve the use of reagents such as 2,3-dimethyl-2,3-dibenzylchroman and tert-butyldimethylsilyl chloride.
    2. Condensation reaction: The next step involves the condensation of the starting material with a compound known as (4R)-4-methoxytetrahydrofuran-2-carboxaldehyde.
      This condensation reaction is carried out in the presence of a catalyst, such as sodium hydroxide, and results in the formation of Xxxx.
    3. Protection of the alcohol group: After the condensation reaction is complete, the alcohol group of Xxxx is protected with a tosyl group.
      This is done by treating Xxxx with a reagent known as tosyl chloride in the presence of a base, such as pyridine.
    4. Deprotection of the alcohol group: The tosyl group is then removed from Xxxx to reveal the alcohol group.
      This is done by treating Xxxx with a reagent known as hydrazine in the presence of a solvent, such as ethanol.
    5. Acylation: The final step involves the acylation of Xxxx with a compound known as benzoyl chloride.
      This reaction is carried out in the presence of a catalyst, such as pyridine, and results in the formation of the final product, Xxxx.

    Overall, the synthetic routes of Xxxx are highly complex and involve several steps and various reagents.
    The synthesis of Xxxx requires a good understanding of organic chemistry and the use of specialized equipment and techniques.
    The compound is used as a synthetic intermediate in the production of various chemicals, pharmaceuticals, and other products, making it an important compound in the chemical industry.


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