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Introduction
11117-11-6, also known as N,N-dimethyl-1,4-benzoxazepin-3-amine, is a commonly used building block in the pharmaceutical industry.
It is used in the synthesis of various drug compounds and is known for its ability to enhance flavor in food products.
The synthetic routes for 11117-11-6 can vary depending on the desired product and the reactants used in the synthesis.
In this article, we will explore some of the most commonly used synthetic routes for 11117-11-6 and their applications in the chemical industry.
Synthetic Route 1: Nitric Oxide Route
One of the most common methods of synthesizing 11117-11-6 is through the nitric oxide route.
This route involves the reaction of N-phenyl-1,4-benzoxazepine-3-amine with nitric oxide in the presence of a catalyst.
The reaction results in the formation of 11117-11-6 and water.
The process is highly efficient, with a yield of over 90%.
This route is widely used in the pharmaceutical industry for the synthesis of various drug compounds.
Synthetic Route 2: Phenylglyoxal Route
Another commonly used synthetic route for 11117-11-6 is the phenylglyoxal route.
This route involves the reaction of N-phenyl-1,4-benzoxazepine-3-amine with phenylglyoxal under acidic conditions.
The reaction results in the formation of 11117-11-6 and water.
The process is highly efficient, with a yield of over 90%.
This route is also widely used in the pharmaceutical industry for the synthesis of various drug compounds.
Synthetic Route 3: KF/H2O2 Route
The KF/H2O2 route is a commonly used method for the synthesis of 11117-11-6.
This route involves the reaction of N-phenyl-1,4-benzoxazepine-3-amine with potassium permanganate in the presence of hydrogen peroxide in a polar solvent.
The reaction results in the formation of 11117-11-6 and water.
The process is highly efficient, with a yield of over 90%.
This route is also widely used in the pharmaceutical industry for the synthesis of various drug compounds.
Advantages of Synthetic Routes
The synthetic routes for 11117-11-6 have several advantages in the chemical industry.
One of the major advantages is their high yield, with all three routes delivering over 90% yield.
This means that the synthesis of 11117-11-6 is highly efficient and cost-effective.
Additionally, these routes are highly versatile and can be used in the synthesis of a wide range of drug compounds, making them valuable tools in the pharmaceutical industry.
Conclusion
In conclusion, the synthetic routes for 11117-11-6 are highly efficient and versatile in the chemical industry.
The nitric oxide, phenylglyoxal, and KF/H2O2 routes all offer high yields and are widely used in the synthesis of various drug compounds.
The advantages of these routes make them valuable tools in the chemical industry and their use is expected to increase in the near future.