The Synthetic Routes of 1-methyltetrahydro-2(1H)-pyrimidinone(SALTDATA: FREE)

1-Methyltetrahydro-2(1H)-pyrimidinone, also known as SALTDATA, is a compound that is widely used in the chemical industry.
It is a synthetic chemical intermediate that is used in the production of a variety of chemical products, including pharmaceuticals, agrochemicals, and materials.

There are several synthetic routes that can be used to produce 1-methyltetrahydro-2(1H)-pyrimidinone.
The most common method is the reaction of 2,4-diamino-6-hydroxypyrimidine with methyl iodide in the presence of a base, such as sodium hydroxide.
This reaction results in the formation of 1-methyltetrahydro-2(1H)-pyrimidinone, along with the corresponding sodium salt of the compound.

Another synthetic route to 1-methyltetrahydro-2(1H)-pyrimidinone involves the reaction of 2,4-diamino-6-hydroxypyrimidine with methyl bromide in the presence of a Lewis acid catalyst, such as zinc chloride.
This reaction also results in the formation of the 1-methyltetrahydro-2(1H)-pyrimidinone, along with the corresponding methyl bromide salt.

1-Methyltetrahydro-2(1H)-pyrimidinone can also be produced by the reduction of 2,4-diamino-6-nitro-pyrimidine using a reducing agent, such as lithium aluminum hydride or hydrogen in the presence of a solvent, such as diethyl ether.
This reaction results in the formation of 1-methyltetrahydro-2(1H)-pyrimidinone, along with the corresponding lithium or hydrogen salt of the compound.

In the final step of the synthesis of 1-methyltetrahydro-2(1H)-pyrimidinone, the corresponding sodium, lithium or hydrogen salt is typically removed by treating the compound with a mineral acid, such as hydrochloric acid or sulfuric acid.
This step is necessary to produce a pure sample of the synthetic chemical intermediate.

1-Methyltetrahydro-2(1H)-pyrimidinone is an important synthetic chemical intermediate that is widely used in the production of a variety of chemical products.
Its synthetic routes involve the reaction of 2,4-diamino-6-hydroxypyrimidine with methyl iodide, methyl bromide or 2,4-diamino-6-nitro-pyrimidine using various catalysts and reducing agents.
The synthetic intermediate is further purified by treating it with a mineral acid, such as hydrochloric acid or sulfuric acid, to remove the corresponding salt.