The Synthetic Routes of 1-(6-CHLOROPYRIDAZIN-3-YL)PIPERIDINE-4-CARBOXAMIDE

The Synthetic Routes of 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide: A Comprehensive Review

1. Introduction
   1.
   1 Background on 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide
   1.
   2 Significance of synthetic routes
   1.
   3 Objective of the article
2. Overview of 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide
   2.
   1 Chemical structure of 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide
   2.
   2 Properties and uses of 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide
3. Synthetic routes for 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide
   3.
   1 Route 1: via N-Alkylazidolation of Pyrrole
   3.
   1.
   1 Catalysts and conditions
   3.
   1.
   2 Mechanism
   3.
   1.
   3 Advantages and disadvantages
   3.
   1.
   4 Recent developments and modifications
   3.
   2 Route 2: via Terminal Alkylenation of Pyrroline Derivatives
   3.
   2.
   1 Catalysts and conditions
   3.
   2.
   2 Mechanism
   3.
   2.
   3 Advantages and disadvantages
   3.
   2.
   4 Recent developments and modifications
   3.
   3 Route 3: via Direct Amination of Pyrrole with Ammonia or Amine
   3.
   3.
   1 Catalysts and conditions
   3.
   3.
   2 Mechanism
   3.
   3.
   3 Advantages and disadvantages
   3.
   3.
   4 Recent developments and modifications
4. Comparison of Synthetic Routes for 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide
   4.
   1 Comparison of reaction conditions, yield, and selectivity
   4.
   2 Comparison of safety and environmental impact
   4.
   3 Comparison of cost and scalability
   4.
   4 Comparison of the availability of reagents and ease of operation
5. Future prospects for the synthesis of 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide
   5.
   1 Potential modifications and improvements
   5.
   2 Potential applications in drug discovery and development
   5.
   3 Potential environmental and safety concerns
6. Conclusion
   6.
   1 Summary of the article
   6.
   2 Implications for chemical industry and research
   6.
   3 Call to action for further research and development
7. References

Appendix A: List of abbreviations
Appendix B: Glossary of terms

1. Introduction

1.
1 Background on 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide

1.
1.
1 Overview of 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide

1.
1.
2 Importance of 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide in chemical industry

1.
2 Significance of synthetic routes

1.
2.
1 Importance of the synthetic routes for the production of 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide

1.
2.
2 Significance of the synthetic routes for the cost and efficiency of production

1.
3 Objective of the article

1.
3.
1 To provide a comprehensive review of the synthetic routes for 1-(6-Chloropyridazine-3-yl)Piperidine-4-carboxamide