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    Home > Medical News > Medical World News > The Synthetic Routes of 1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester

    The Synthetic Routes of 1,2-Dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester

    • Last Update: 2023-05-05
    • Source: Internet
    • Author: User
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    The chemical industry is a vast and complex field, with countless chemicals and compounds being synthesized and produced on a large scale.
    One such compound is 1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester, a synthetic chemical with a unique set of properties and potential applications.
    The synthesis of this compound is a complex process that involves several steps, and there are several different synthetic routes that can be used to produce it.


    One of the most common synthetic routes for 1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester involves the reaction of 2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid with ethylene oxide.
    This reaction is typically carried out in the presence of a strong acid catalyst, such as sulfuric acid or phosphoric acid, and the resulting product is a colored liquid with a distinctive odor.


    Another synthetic route for 1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester involves the reaction of 2-amino-6-(trifluoromethyl)-3-pyridinecarboxylic acid with ethyl bromide in the presence of a strong base, such as sodium hydroxide.
    This reaction results in the formation of the desired ester, as well as a corresponding amine, which can be distilled off to purify the product.


    A third synthetic route for 1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester involves the reaction of 2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid with ethyl iodide in the presence of a solvent, such as dichloromethane or chloroform.
    This reaction is typically carried out at a lower temperature, and the resulting product is a pale yellow liquid with a mild odor.


    Whichever synthetic route is used, the resulting product is typically purified through a series of chromatography and crystallization steps to remove any impurities and produce a pure sample of 1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester.
    This compound can then be used in a variety of applications, including pharmaceuticals, agrochemicals, and other industrial processes.


    In conclusion, the synthetic routes of 1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinecarboxylic acid ethyl ester are complex and varied, and depend on a variety of factors, including the available starting materials, the desired product, and the desired purity and yield.
    Regardless of the route used, the resulting product is typically a valuable synthetic intermediate that can be used in a variety of applications.


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