The Synthetic Routes of 1,2-Benzenedicarboxylic acid, 3-nitro-, 1,2-dimethyl ester

1,2-Benzenedicarboxylic acid, 3-nitro-, 1,2-dimethyl ester is an important intermediate in the production of a variety of chemical products, including dyes, pharmaceuticals, and plastics.
The synthetic routes for this compound can vary depending on the specificapplication and the goals of the synthesis.

One common synthetic route for 1,2-benzenedicarboxylic acid, 3-nitro-, 1,2-dimethyl ester is through the reaction of 3-nitrobenzaldehyde with dimethyl sebacate in the presence of a base, such as sodium hydroxide.
This reaction results in the formation of the nitro ester, which can then be hydrolyzed to form the desired carboxylic acid.

Another synthetic route involves the reaction of 3-nitrobenzene with potassium permanganate in the presence of a solvent, such as water.
This reaction results in the formation of the nitrobenzene, which can then be reduced to form the desired carboxylic acid using a reducing agent, such as lithium aluminum hydride.

Yet another synthetic route involves the reaction of 1,2-benzendicarboxylic acid with 3-nitro-2-aminopropane in the presence of a base, such as cesium carbonate.
This reaction results in the formation of the nitro ester, which can then be hydrolyzed to form the desired carboxylic acid.

The choice of synthetic route will depend on the specific application and the goals of the synthesis.
For example, if the goal is to produce a large quantity of the compound for use as a chemical intermediate, a more efficient and cost-effective synthetic route may be chosen.
On the other hand, if the goal is to synthesize the compound for use in a specific application, such as in the production of a medication, the synthetic route may be tailored to meet the specific requirements of that application.

Overall, the synthetic routes for 1,2-benzenedicarboxylic acid, 3-nitro-, 1,2-dimethyl ester can vary depending on the specific application and the goals of the synthesis.
These routes can include the reaction of 3-nitrobenzaldehyde with dimethyl sebacate, the reaction of 3-nitrobenzene with potassium permanganate, and the reaction of 1,2-benzenedicarboxylic acid with 3-nitro-2-aminopropane.
The choice of synthetic route will depend on the specific application and the goals of the synthesis.