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1-(2,4-Dichlorophenyl)-1-propanone, also known as 2,4-dichlorophenyl acetate, is a synthetic compound that is commonly used as a building block in organic synthesis.
It can be used to synthesize a wide variety of chemicals, including propionates, acetates, and other derivatives.
The synthetic routes of 2,4-dichlorophenyl acetate can be broadly classified into two categories: synthetic routes using natural sources and synthetic routes using chemical methods.
Synthetic routes using natural sources:
One of the most common ways to synthesize 2,4-dichlorophenyl acetate is through the use of natural sources, such as biomass.
The production of 2,4-dichlorophenyl acetate from biomass involves the use of microorganisms, such as yeast, to convert the biomass into the desired compound.
This process is known as fermentation.
Fermentation is a widely used method for the production of a variety of chemicals, including 2,4-dichlorophenyl acetate.
Synthetic routes using chemical methods:
Another way to synthesize 2,4-dichlorophenyl acetate is through the use of chemical methods, such as the Sharpless epoxidation and the Glassman-Kim reaction.
The Sharpless epoxidation is a widely used method for the synthesis of 2,4-dichlorophenyl acetate.
This method involves the use of a metal catalyst, such as silver or copper, to convert the starting material into the desired compound.
The Glassman-Kim reaction is another method that can be used to synthesize 2,4-dichlorophenyl acetate.
This method involves the use of a palladium catalyst and is commonly used in the pharmaceutical industry.
Another synthetic route is via the reaction of 2,4- dichlorophenylamine with acetyl chloride in the presence of a base such as sodium hydroxide.
Advantages of synthetic routes:
The synthetic routes of 2,4-dichlorophenyl acetate offer several advantages over traditional methods of production.
One of the main advantages is that they allow for the large-scale production of the compound, which is necessary for industrial applications.
They also allow for a high degree of control over the synthesis process, which is important for ensuring the purity and consistency of the final product.
Disadvantages of synthetic routes:
However, the synthetic routes of 2,4-dichlorophenyl acetate also have some disadvantages.
One of the main disadvantages is that they can be more time-consuming and expensive than traditional methods of production.
They also require the use of specialized equipment and reagents, which can be costly.
Conclusion:
1-(2,4-Dichlorophenyl)-1-propanone is a widely used synthetic compound that can be synthesized through a variety of methods.
The most common synthetic routes include those using natural sources such as fermentation and chemical methods such as the Sharpless epoxidation and the Glassman-Kim reaction.
These routes offer several advantages over traditional methods of production, such as large-scale production and high degree of control over the synthesis process.
However, they also have some disadvantages, such as being more time-consuming and expensive than traditional methods.