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    Home > Active Ingredient News > Drugs Articles > The Synthetic Routes of 1,1-Dimethylethyl N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate

    The Synthetic Routes of 1,1-Dimethylethyl N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate

    • Last Update: 2023-05-13
    • Source: Internet
    • Author: User
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    1,1-Dimethylethyl N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate is a synthetic compound commonly used in the chemical industry.
    It is a derivative of N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamic acid and is a useful intermediate for the synthesis of various pharmaceuticals, agrochemicals, and other industrial products.


    The synthesis of 1,1-Dimethylethyl N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate involves several steps, including the synthesis of the corresponding amino acid, the activation of the amino acid with a carbonyl compound, and the binding of the amino acid to a urea group.


    The synthesis of the amino acid, N-[(1R,2S,5S)-2-amino-5-(dimethylamino)cyclohexyl]carbamic acid, involves the use of several chemical reagents and is typically carried out in several stages.
    The synthesis of the dimethylamino group can be accomplished using methods such as hydrolysis of dimethylammonium salts or the reduction of dimethylamine with lithium aluminum hydride.


    Once the amino acid has been synthesized, it can be activated with a carbonyl compound, such as carbon dioxide or methyl iodide, to form an activated carbonyl compound.
    This activated carbonyl compound can then react with the amino group of the amino acid to form an amidine.


    Finally, the amidine can be bound to a urea group to form 1,1-Dimethylethyl N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate.
    This reaction can be carried out using methods such as the Hunsdiecker reaction or the Wittig reaction.


    Overall, the synthesis of 1,1-Dimethylethyl N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate involves several steps, but it is a relatively straightforward synthesis that can be carried out using standard chemical techniques.
    The compound is a useful intermediate in the synthesis of various pharmaceuticals and industrial products, making it an important compound in the chemical industry.



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