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1,1-Dimethylethyl 4-[[4-[[[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]methyl]-1-piperazinecarboxylate, also known as Compound X, is an organic compound that is used in various industrial processes.
The synthesis of this compound can be achieved through a variety of methods, which are referred to as synthetic routes.
One of the most common synthetic routes for Compound X involves a multi-step reaction process.
The first step involves the synthesis of a substituted aniline derivative, which is then reacted with a substituted carbonyl chloride in the presence of a solvent such as dichloromethane.
The reaction is then quenched with an aqueous solution of sodium bicarbonate, and the resulting product is extracted with a solvent such as ethyl acetate.
The organic layer is then dried and concentrated, and the resulting residue is purified using high-performance liquid chromatography (HPLC) to obtain the desired product.
Another synthetic route for Compound X involves a one-pot reaction process.
In this process, a mixture of the substituted aniline derivative and substituted carbonyl chloride is reacted in the presence of a catalyst such as cesium carbonate.
The reaction is then quenched with an aqueous solution of sodium bicarbonate, and the resulting product is extracted with a solvent such as ethyl acetate.
The organic layer is then dried and concentrated, and the resulting residue is purified using HPLC to obtain the desired product.
A third synthetic route for Compound X involves a two-step reaction process.
In the first step, a substituted aniline derivative is reacted with a substituted malonate derivative in the presence of a solvent such as N,N-dimethylformamide.
The resulting product is then reacted with a substituted carbonyl chloride in the presence of a catalyst such as triethylamine.
The reaction is then quenched with an aqueous solution of sodium bicarbonate, and the resulting product is extracted with a solvent such as ethyl acetate.
The organic layer is then dried and concentrated, and the resulting residue is purified using HPLC to obtain the desired product.
The choice of synthetic route depends on various factors, including cost, efficiency, and accessibility of raw materials.
It is important to note that the synthesis of Compound X requires the use of hazardous chemicals and should be carried out by trained professionals in a controlled laboratory environment.
In conclusion, the synthetic routes for 1,1-Dimethylethyl 4-[[4-[[[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]methyl]-1-piperazinecarboxylate are diverse, and the selection of a particular route depends on various factors.
The resulting product is a valuable intermediate in the production of various chemicals and pharmaceuticals and is widely used in the chemical industry.
The synthesis of Compound X is a challenging task that requires the use of specialized equipment and the expertise of trained professionals.