The study revealed abnormal brain structure connections and functional connections in people with high schizophrenic traits.

Schizophrenia is a complex, heavy-duty mental brain disease in which patients have a wide range of cognitive, emotional, social dysfunction and brain structure changes.
recent studies have shown that "continuous" research methods can integrate disease symptom levels and psychotic-related traits into changes in risk levels during the development of the disease.
-splitting traits refer to psychotic traits that are prevalent among the general population below the clinical diagnostic threshold.
the study of schizophrenic traits can not only provide theoretical guidance on understanding the esoteric and clinical variability associated with susceptible schizophrenia spectrum, but also help to understand the complexity of esoteric patterns in clinical and subclinical groups.
changes in brain structure and functional connections associated with disease are ideomorgasms of mental illness.
, little is known about whether the divisive trait is associated with specific changes in brain connectivity.
Chen Chuyu, a researcher at the Mental Health Key Laboratory of the Institute of Psychology of the Chinese Academy of Sciences and a researcher in the Applied Cognitive Neuroscience Laboratory, and his team examined changes in brain structure and functional connections associated with schizophrenic traits.
study recruited 87 individuals with high schizophrenic traits and 122 individuals with low schizophrenic traits to have their resting states and dispersion imaging scans. the
study showed that the probability of task control network and structural connection within the default network increased, while the variation of functional connection between the default network, auditory network and sub-cortical network increased, stability decreased, and the average functional connection strength of sensory motion network, default network and task control network decreased.
highly divisive traits show compensatory and defective connection changes, mainly related to the default network, task control network, and sensory motion network.
results point to adaptive changes in the potential brain connectivity of individuals with high schizophrenic traits and provide a possible neurobiological basis for the thesis of connectivity compensation disorders for schizophrenia spectrum disorders.
study the brain structure associated with schizophrenic traits, especially changes in the subsurfic region.
addition, Chen's team is conducting studies to see whether these observed changes are specific to the characteristics of people with divisive traits or overlap with the performance of people with other subclinical characteristics.
research work is supported by the National Key Research and Development Project, the Beijing Municipal Science and Technology Commission, the Leading Talent Training Project of "Science and Technology Beijing", the Strategic Key Research Program (B) of the Chinese Academy of Sciences, and the Mental Health Key Laboratory of the Chinese Academy of Sciences.
study was published online online in Psychological Medicine.
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