The study results of cardiovascular disease research are interpreted!

In this paper, the small compilation of a number of research results, together focus on scientists in the field of cardiovascular disease research achievements, share to everyone! Photo Credit: CC0 Public Domain BMJ: One egg a day or does not increase the body's risk of cardiovascular disease doi: 10.1136/bmj.m513, a recent study published in the international journal BMJ, by scientists at the University of California, N.J., A moderate intake of eggs (up to one egg per day) is not associated with the body's risk of cardiovascular disease, which is a cheap source of high-quality protein, iron and unsaturated fatty acids, but because of its cholesterol, scientists have been debating the link between egg intake and cardiovascular disease risk for the past decadeA large number of studies have produced inconsistent results, and even previous comprehensive analyses have not provided consistent results, which will undoubtedly lead to further confusionTo assess the association between egg intake and cardiovascular disease risk, researchers needed to measure the dietary and lifestyle factors of the population over a long period of time, and it was important to consider the effects of eggs on the body's cardiovascular risk compared to animal and plant dietsFor the study, researchers used data from repeated diets from participants over a 32-year period beginning in 1980 to investigate the association between egg intake and cases of cardiovascular disease, including non-lethal heart attacks, fatal coronary heart disease and stroke; A total of 83,349 female nurses between the ages of 30 and 35, 90,214 female nurses between the ages of 25 and 44, and 42,055 male health professionals between the ages of 40 and 75 were not involved in cardiovascular disease, type 2 diabetes and cancer at the start of the studyCell: Shocked! Studies have found that gut microbial metabolites increase the risk of cardiovascular disease! Doi: 10.1016/j.cell.2020.02.016 Researchers at the Cleveland Clinic have identified a by-product of an intestinal microorganism, phenyl acetaminophen (PAG), that is associated with the development of cardiovascular disease, including heart disease, stroke and deathThe study was recently published in the journal CellPhenylalanine is an amino acid found in many foods, including plant and animal-based protein sources such as meat, beans and soyThe team, led by Stanley Hazen, director of the Department of Cardiovascular and Metabolic Sciences at the Lerner Institute and co-director of the Department of Prevention and Rehabilitation at the Miller Family Cardiovascular And Thoracic Institute, found that when phenylalanine is broken down by microbes in the gut, its by-products (metabolites) PAG eventually appear in the blood, leading to heart diseaseOver the past decade, researchers say, there has been a growing body of data showing that gut microbes play an important role in health, especially when it is associated with heart disease, and they have found that PAG in the blood increases the risk of cardiovascular disease in several different waysBMJ: More than 400,000 people followed up on the results of 13 years Fish oil supplements or directly related to the overall mortality and reduced risk of cardiovascular disease death! Doi: 10.1136/bmj.m456, a study published in the international journal BMJ, scientists from southern medical universities and other institutions found that regular intake of supplements or reduced the risk of death and cardiovascular events, such as heart attacks and strokes, was found; Fish oil is the most popular dietary supplement in the UK and other developed countries, and there is research evidence that omega-3 fatty acids in fish oil can help prevent cardiovascular disease and reduce mortality, but researchers still lack clear evidence; to shed more into the link, researchers analyzed data from the UK bio-sample pool, which included 427,678 men and women aged between 40 and 6 without cardiovascular disease or cancer4 PNAS: A new breakthrough in cardiovascular disease treatment: 10.1073/pnas.1911243117, a recent study published in the international journal PNAS, a researcher from the University of Otago has made an innovative discovery that paves the way for the treatment of cardiovascular diseases, including hypertensionDrMartinieu Fros of the Department of Physiology, who led the study, found new mechanisms for regulating blood pressureSpecifically, he discovered a new mechanism that contributes to "blood flow-mediated dilation", in which the arteries expand as blood flow increasesOur study found a new mechanism that helps fluid-mediated expansion and reveals how force perception occurs at the molecular level of cells; the researchers say the ability of cells to sense mechanical signals is important for tactile and pain perception, which is related to hearing but also to blood pressure regulationDiabetogia: Special intestinal hormones may increase an individual's risk of cardiovascular disease: 10.1007/s00125-05093-9 In a recent study published in the international journal Diabetogia, scientists from the University of Lund and other institutions found that high levels of gastrointestinal hormone GIP in the blood are directly linked to increased risk of cardiovascular diseaseAs we all know, the gut hormones GIP and GLP-1 are essential for the production of insulin in the pancreas, which when we eat and produce and regulate the production of insulin, nutrient intake, appetite and energy use in the gut when we eat, and can also serve as important therapeutic targets to help develop new treatments for hyperglycemia in people with type 2 diabetes In addition to lowering blood sugar, the drug therapy that stimulates GLP-1 release also protects the body from cardiovascular disease Researcher Martin Magnusson says a growing body of research suggests that GIP or the expression that directly stimulates GIP receptors may have negative cardiovascular effects and induce cardiovascular disease in the body For the study, researchers used blood samples and data from two large population research programs to try to clarify a direct link between GIP and GLP-1 and the risk of cardiovascular disease prognosis and premature death Photo credit: CC0 Public Domain 6 Lancet Sub-Journal: Watch Out! Excess fat in the body may trigger cardiovascular disease and type 2 diabetes! Doi: 10.1016/S2213-8587 (19) 30084-1, a study published in the international journal The Lancet Diabetes and Endocrinology, from the University of Surrey in the United Kingdom, by studying excess fat in the body or a key driver of cardiovascular disease and type 2 diabetes In the article, the researchers reviewed the role of visceral fats and ectopic fats in disease pathophysiology, and suggested measuring these types of fats in practice The accumulation of body fat usually occurs around important organs, which is also considered visceral or intra-abdominal fat, the accumulation of these fats will increase the storage of fat in the liver, heart, pancreas and skeletal muscle, excess of internal organs and ectopic fat will affect the body's metabolism, thus inducing cardiovascular disease and type 2 diabetes, to determine the content of these fats or to improve the prediction, treatment and prevention strategies of both diseases However, without complex techniques such as computed tomography (CT) or magnetic resonance imaging (MRI), it is difficult for researchers to determine the location of these types of fat within the body; Nat Med: A special gut bacteria is expected to reduce cardiovascular disease risk in 50% of the population: 10.1038/s41591-019-0495-22007, scientists at the University of Leuven and other institutions have discovered the gut bacteria Akkermansia muc muc The beneficial effects of ininifiphila may slow the incidence of obesity and type 2 diabetes in mice, and the use of the bacteria's "pasteurization form" (inactivated form) may even protect the body against a variety of cardiovascular risk factors, such as insulin tolerance, hypercholesterolemia, or the accumulation of fat in fatty tissue, compared to other intestinal flora Based on previous research, researchers at the University of Leuven and others recently conducted a clinical trial to inject the gut bacteria Akkermansia muciniphila into the human body to see the beneficial effects; In the article, the researchers injected Akkermansia into overweight or obese volunteer bodies, all of whom showed insulin tolerance (pre-type type 2 diabetes) and metabolic syndrome, in other words, higher levels of multiple cardiovascular risk factors in the body, and the volunteers were randomly divided into three groups, namely comfort units, live bacteria and papyresic treatment groups, all of whom were asked not to change their eating habits and physical activity, and Akkersia was offered nutritional supplements 8: Cholesterol intake of more eggs increases the risk of cardiovascular disease and early death: 10.1001/jama.2019.1572 Nutrition experts from the University of Massachusetts at Lowell say the risk of heart disease and death increases as the number of eggs a person eats increases Researchers tracked the diet, health and lifestyle of nearly 30,000 adults across the country for 31 years and found a link between cholesterol and poor health from high-volume egg consumption Catherine Tucker, professor of biomedical and nutritional sciences at Umass Lowell's Zuckerberg School of Health Sciences, led the study, which was published in the Journal of the American Medical Association The findings come at a time when egg consumption in the United States is rising According to the U.S Department of Agriculture, Americans ate an average of 279 eggs a year in 2017, up from 254 in 2012 Current Dietary Guidelines in the United States do not give advice on how many eggs everyone should eat each day Tucker says the guidelines are updated every five years, but do not include this one because nutrition experts have begun to believe that the driver behind high cholesterol levels is saturated fat, not eggs However, she says that by 2015, the guidelines do recommend that individuals consume no more than 300 milligrams of cholesterol per day Nature: Why does adequate sleep reduce the risk of cardiovascular disease? doi: 10.1038/s41586-019-0948-2 Getting adequate sleep is key to health, and studies show that lack of sleep increases the risk of serious problems such as cardiovascular disease Now researchers at Massachusetts General Hospital (MGH) have discovered a way to sleep to prevent the formation of atherosclerosis plaques In a paper published in the journal Nature, the authors describe the mechanism by which lack of sleep increases the production of inflammatory white blood cells known to be the main cause of atherosclerosis Sleep helps regulate the production of the bone marrow of inflammatory cells and the health of blood vessels, the researchers said, and instead, sleep interruptions disrupt control of the production of inflammatory cells, leading to more inflammation and heart disease, and we have identified how a hormone in the brain that controls awakening controls the processes in the bone marrow and prevents cardiovascular disease To study the extent to which lack of sleep increases atherosclerosis, Swirski's team performed atherosclerosis on genetically programmed mice to repeatedly interrupt sleep, similar to the experience of waking up with noise or discomfort Although sleep deprived mice of no change in weight, cholesterol levels or glucose tolerance, patients with normal sleep, sleep-crushing and higher levels of mononucleosis and neutrophils were sleep-deprived Nature: Shocked! In a new study, researchers from Massachusetts General Hospital (MGH) identified an important checkpoint in dietary metabolism: a group of cells in the small intestine that regulate metabolism and accelerate the production of cardiovascular disease 10.1038/s41586-0849-9 This group of cells slows down metabolism, thereby increasing the intake of food stored as fat, rather than converting it rapidly into energy They found that mice without these cells were able to eat a diet high in fat and sugar without diseases such as obesity, diabetes, high blood pressure and heart disease The findings were published in the journal Nature After eating food, the researchers say, the body can convert energy into calories and burn it quickly, or it can convert food into fat and store it for later use We often talk about 'high metabolism' people who seem to be able to eat whatever they want without gaining weight, while others fight obesity These cells are known for their function in the immune system and also appear to play an important role in metabolic selection (BioValleyBioon.com) Bio Valley For More Great Counts! 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