The study found potential new treatments for diabetes
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Last Update: 2020-12-18
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Source: Internet
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Author: User
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the latest issue of the U.S. journal
shows that activating vitamin D subjects can help repair damaged islet beta cells and could be a new treatment for diabetes.
previous studies have shown that people who have higher levels of vitamin D are at lower risk of developing diabetes. But the medical community has not been clear about the rationale.
islet beta cells are islet cells that secrete insulin and regulate blood sugar levels. Impaired islet beta cell function leads to absolute or relative deficiency of insulin secretion, leading to diabetes.
Researchers at the Salk Institute of Biology in the United States and the University of Sydney in Australia used embryonic stem cells in a petri dish to grow islet beta cells, and found that a compound iBRD9 activates vitamin D subjects, increasing the expression of certain anti-inflammatory genes, thereby improving the survival of islet beta cells.
, senior author of the study and a professor at the Salk Institute for Biological Research, explains that diabetes is a disease caused by an inflammatory response. Vitamin D subjects can be involved in regulating inflammatory responses and improving the survival of islet beta cells.
animal experiments conducted by researchers also found that the compound returned to normal blood sugar levels in mice with diabetes after activating the vitamin D complex.
researchers say they have yet to find any new compounds that could have side effects in mice, but further research is needed to get into clinical trials. The treatment is expected to be used to treat other diseases that require vitamin D enhancement, such as pancreatic cancer. (Source: Xinhua News Agency Zhou Zhou)
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