The Safety of tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate

Tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate is a chemical compound that is used in various industrial applications, including as a building block for the synthesis of other chemicals and as a intermediate in the production of agrochemicals, pharmaceuticals, and personal care products.

Safety Profile of Tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate

Tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate is considered to be a relatively safe chemical to handle and use in industrial settings, provided that proper safety protocols are followed.
However, it is still important to take necessary precautions and follow safety guidelines to minimize the risk of exposure and ensure the safety of workers and the environment.

Physical and Chemical Properties

Tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate is a yellow or yellowish-green liquid with a characteristic, unpleasant odor.
It is highly soluble in water and is moderately toxic when ingested, inhaled, or when it comes into contact with the skin.

Toxicity and Hazards

Tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate is classified as a Category 3 carcinogen by the International Agency for Research on Cancer (IARC), which means that it is not classifiable as to its carcinogenicity to humans.
While there is some evidence suggesting that it may be carcinogenic, the data is limited and inconclusive.

However, tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate is known to be toxic when ingested, inhaled, or when it comes into contact with the skin.
Ingestion of small amounts of the chemical can cause nausea, vomiting, and abdominal pain, while larger amounts can cause more severe symptoms, such as seizures, respiratory depression, and even death.

When inhaled, the chemical can cause irritation to the respiratory system and can cause symptoms such as coughing, chest pain, and difficulty breathing.
Prolonged exposure to the vapor or mist of the chemical can also cause bronchitis and other respiratory problems.

When tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate comes into contact with the skin, it can cause irritation, redness, and itching.
Prolonged exposure to the chemical can cause more severe symptoms, such as skin ulceration and necrosis.

Handling and Storage of Tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate

Tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate should be handled with caution at all times.
Workers who handle the chemical should wear appropriate personal protective equipment, including gloves, safety glasses, and lab coats.

The chemical should be stored in a cool, dry place and stored away from sources of ignition or heat.
It should be stored in suitable containers, preferably made of impervious materials, such as tin or plastic.

Proper disposal of tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate is also important.
Any waste materials that contain the chemical should be disposed of in accordance with local and national regulations, and should be handled by trained personnel.

Conclusion

Tert-butyl 5-brom