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The Safety of (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine in the Chemical Industry: A Comprehensive Overview
(5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine, also known as EP481, is a chemical compound that is widely used in the pharmaceutical and agrochemical industries.
It is an important intermediate in the synthesis of various drugs and insecticides, and its unique properties make it a valuable chemical building block for a variety of applications.
However, the use of (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine also raises questions about its safety for human health and the environment.
In this article, we will examine the properties of (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine, its uses in industry, and the safety concerns associated with its use.
Properties of (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine
(5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine is a colorless liquid with a distinct, unpleasant odor.
It is highly soluble in water and has a high volatility, meaning that it evaporates quickly at room temperature.
It is also a moderate to strong acid, with a pKa value of around 8.
5, and it is highly reactive to other chemicals.
These properties make it a useful intermediate for the synthesis of other chemicals, but they also raise concerns about its potential for reactivity and toxicity.
Uses of (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine in Industry
(5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine is used in the production of various drugs and insecticides, including some widely used medications and insecticides.
It is also used in the production of other chemicals, such as dyes, solvents, and polymers.
Due to its unique properties, (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine is an important intermediate in the synthesis of these chemicals, and it plays a critical role in the production of many everyday products.
Safety Concerns of (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine
Despite its widespread use in industry, (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine has been associated with various safety concerns.
Some studies have shown that it can cause skin irritation and allergic reactions in humans, while others have suggested that it may be toxic to aquatic life and other organisms.
There is also some evidence to suggest that it may be harmful if ingested, inhaled, or if it comes into contact with the skin.
Additionally, (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine is classified as a Category 3 carcinogen by the International Agency for Research on Cancer (IARC), meaning that it is possibly carcinogenic to humans.
Regulatory Standards for (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine
In order to ensure the safety of workers and the general public, regulatory agencies such as the Environmental Protection Agency (EPA) and the Occupational Safety and Health Administration (OSHA) have established strict guidelines for the handling and use of (5-Chloro-pyrimidin-2-yl)-cyclopropyl-amine.
These guidelines include required protective equipment, proper storage and